Monitoring of ultra- and diafiltration processes by Kalman-filtered Raman measurements

Monitoring the protein concentration and buffer composition during the Ultrafiltration/Diafiltration (UF/DF) step enables the further automation of biopharmaceutical production and supports Real-time Release Testing (RTRT). Previously, in-line Ultraviolet (UV) and Infrared (IR) measurements have bee...

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Detalles Bibliográficos
Autores principales: Rolinger, Laura, Hubbuch, Jürgen, Rüdt, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883314/
https://www.ncbi.nlm.nih.gov/pubmed/36651972
http://dx.doi.org/10.1007/s00216-022-04477-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883314/
https://www.ncbi.nlm.nih.gov/pubmed/36651972
http://dx.doi.org/10.1007/s00216-022-04477-7

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