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Mitochondrial phosphoenolpyruvate carboxykinase promotes tumor growth in estrogen receptor‐positive breast cancer via regulation of the mTOR pathway

BACKGROUND: Tumor cells may aberrantly express metabolic enzymes to adapt to their environment for survival and growth. Targeting cancer‐specific metabolic enzymes is a potential therapeutic strategy. Phosphoenolpyruvate carboxykinase (PEPCK) catalyzes the conversion of oxaloacetate to phosphoenolpy...

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Detalles Bibliográficos
Autores principales:	Hsu, Hui‐Ping, Chu, Pei‐Yi, Chang, Tsung‐Ming, Huang, Kuo‐Wei, Hung, Wen‐Chun, Jiang, Shih Sheng, Lin, Hui‐You, Tsai, Hui‐Jen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	RESEARCH ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883444/ https://www.ncbi.nlm.nih.gov/pubmed/35757841 http://dx.doi.org/10.1002/cam4.4969

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