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Kinetic fingerprinting of metabotropic glutamate receptors

Dimeric metabotropic glutamate receptors (mGluRs) are abundantly expressed in neurons. In mammals, eight subunit isoforms, mGluR1-8, have been identified, forming the groups I, II, and III. We investigated receptor dimerization and kinetics of these mGluR isoforms in excised membrane patches by FRET...

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Detalles Bibliográficos
Autores principales: Kukaj, Taulant, Sattler, Christian, Zimmer, Thomas, Schmauder, Ralf, Benndorf, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883448/
https://www.ncbi.nlm.nih.gov/pubmed/36707695
http://dx.doi.org/10.1038/s42003-023-04468-z