TPX2 enhances the transcription factor activation of PXR and enhances the resistance of hepatocellular carcinoma cells to antitumor drugs

The pregnane X receptor (PXR) is an important regulator of hepatocellular carcinoma cellular resistance to antitumor drugs. Activation of PXR was modulated by the co-regulators. The target protein for the Xenopus plus end-directed kinesin-like protein (Xklp2) known as TPX2 that was previously consid...

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Detalles Bibliográficos
Autores principales: Wang, Hongbo, Chu, Fang, Zhang, Xiao-feng, Zhang, Peng, Li, Li-xin, Zhuang, Yun-long, Niu, Xiao-feng, He, Xi, Li, Zhi-jie, Bai, Ying, Mao, Da, Liu, Zhen-wen, Zhang, Da-li, Li, Bo-an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883482/
https://www.ncbi.nlm.nih.gov/pubmed/36707511
http://dx.doi.org/10.1038/s41419-022-05537-7

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