MME(+) fibro-adipogenic progenitors are the dominant adipogenic population during fatty infiltration in human skeletal muscle

Fatty infiltration, the ectopic deposition of adipose tissue within skeletal muscle, is mediated via the adipogenic differentiation of fibro-adipogenic progenitors (FAPs). We used single-nuclei and single-cell RNA sequencing to characterize FAP heterogeneity in patients with fatty infiltration. We i...

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Detalles Bibliográficos
Autores principales: Fitzgerald, Gillian, Turiel, Guillermo, Gorski, Tatiane, Soro-Arnaiz, Inés, Zhang, Jing, Casartelli, Nicola C., Masschelein, Evi, Maffiuletti, Nicola A., Sutter, Reto, Leunig, Michael, Farup, Jean, De Bock, Katrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883500/
https://www.ncbi.nlm.nih.gov/pubmed/36707617
http://dx.doi.org/10.1038/s42003-023-04504-y

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