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Genomic landscape of non‐small‐cell lung cancer with methylthioadenosine phosphorylase (MTAP) deficiency

INTRODUCTION: New treatment strategies for advanced non‐small‐cell lung carcinoma (NSCLC) include synthetic lethality targets focused on protein arginine methyl transferases such as PRMT5 that exploit the impact of genomic loss of methylthioadenosine phosphorylase (MTAP). METHODS: Twenty nine thousa...

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Detalles Bibliográficos
Autores principales:	Ashok Kumar, Prashanth, Graziano, Stephen L., Danziger, Natalie, Pavlick, Dean, Severson, Eric A., Ramkissoon, Shakti H., Huang, Richard S. P., Decker, Brennan, Ross, Jeffrey S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	RESEARCH ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883541/ https://www.ncbi.nlm.nih.gov/pubmed/35747993 http://dx.doi.org/10.1002/cam4.4971

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