Cargando…

Inositol monophosphatase 1 (IMPA1) promotes triple‐negative breast cancer progression through regulating mTOR pathway and EMT process

Triple‐negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, which is characterized by high heterogeneity and metabolic dysregulation. Inositol monophosphatase 1(IMPA1) is critical for the metabolism of inositol, which has profound effects on gene expression and other biolog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Shao‐Ying, Xie, Yi‐Fan, Zhang, Tai‐Mei, Deng, Ling, Liao, Li, Hu, Shu‐Yuan, Zhang, Yin‐Ling, Zhang, Fang‐Lin, Li, Da‐Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	RESEARCH ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883559/ https://www.ncbi.nlm.nih.gov/pubmed/35796646 http://dx.doi.org/10.1002/cam4.4970

Ejemplares similares

Loss-of-function mutation in inositol monophosphatase 1 (IMPA1) results in abnormal synchrony in resting-state EEG
por: Walker, Christopher P., et al.
Publicado: (2019)

Inositol monophosphatase 2 promotes epithelial ovarian cancer cell proliferation and migration by regulating the AKT/mTOR signaling pathway
por: Ablimit, Tangnur, et al.
Publicado: (2022)

Lithium induces autophagy by inhibiting inositol monophosphatase
por: Sarkar, Sovan, et al.
Publicado: (2005)

Characterization of the inositol monophosphatase gene family in Arabidopsis
por: Nourbakhsh, Aida, et al.
Publicado: (2015)

Inositol Monophosphatase: A Bifunctional Enzyme in Mycobacterium smegmatis
por: Goswami, Rajendra, et al.
Publicado: (2018)

Inhibited inositol monophosphatase and decreased myo‐inositol concentration improve wasting in skeletal muscles
por: Lee, Ji‐Hyung, et al.
Publicado: (2020)

Multibody cofactor and substrate molecular recognition in the myo-inositol monophosphatase enzyme
por: Ferruz, Noelia, et al.
Publicado: (2016)

Crystallization and structure of ebselen bound to Cys141 of human inositol monophosphatase
por: Fenn, Gareth D., et al.
Publicado: (2020)

Crosstalk between Ras and inositol phosphate signaling revealed by lithium action on inositol monophosphatase in Schizophyllum commune
por: Murry, Reyna, et al.
Publicado: (2019)

Deficiency of Inositol Monophosphatase Activity Decreases Phosphoinositide Lipids and Enhances TRPV1 Function In Vivo
por: Caires, Rebeca, et al.
Publicado: (2021)

Synaptic Polarity Depends on Phosphatidylinositol Signaling Regulated by myo-Inositol Monophosphatase in Caenorhabditis elegans
por: Kimata, Tsubasa, et al.
Publicado: (2012)

Dimerization of inositol monophosphatase Mycobacterium tuberculosis SuhB is not constitutive, but induced by binding of the activator Mg(2+)
por: Brown, Alistair K, et al.
Publicado: (2007)

A repeat length variation in myo-inositol monophosphatase gene contributes to seed size trait in chickpea
por: Dwivedi, Vikas, et al.
Publicado: (2017)

Sequence-based identification of inositol monophosphatase-like histidinol-phosphate phosphatases (HisN) in Corynebacterium glutamicum, Actinobacteria, and beyond
por: Kulis-Horn, Robert Kasimir, et al.
Publicado: (2017)

DEK promoted EMT and angiogenesis through regulating PI3K/AKT/mTOR pathway in triple-negative breast cancer
por: Yang, Yang, et al.
Publicado: (2017)

SP1-Induced Upregulation of LncRNA AFAP1-AS1 Promotes Tumor Progression in Triple-Negative Breast Cancer by Regulating mTOR Pathway
por: Li, Fangyuan, et al.
Publicado: (2023)

Aurora-A/ERK1/2/mTOR axis promotes tumor progression in triple-negative breast cancer and dual-targeting Aurora-A/mTOR shows synthetic lethality
por: Zhang, Wenfeng, et al.
Publicado: (2019)

IMPA-ICTP School on Moduli of Curves
por: Paz, Leticia, et al.
Publicado: (2017)

Enhanced Activities of Blood Thiamine Diphosphatase and Monophosphatase in Alzheimer's Disease
por: Pan, Xiaoli, et al.
Publicado: (2017)

Dual Target of EGFR and mTOR Suppresses Triple-Negative Breast Cancer Cell Growth by Regulating the Phosphorylation of mTOR Downstream Proteins
por: Ma, Jing, et al.
Publicado: (2023)

Activation of mammalian target of rapamycin (mTOR) in triple negative feline mammary carcinomas
por: Maniscalco, Lorella, et al.
Publicado: (2013)

Role of PTEN, PI3K, and mTOR in Triple-Negative Breast Cancer
por: Prvanović, Mirjana, et al.
Publicado: (2021)

Cytoplasmic cleavage of IMPA1 3′ UTR is necessary for maintaining axon integrity
por: Andreassi, Catia, et al.
Publicado: (2021)

Multi-targeted kinase inhibition alleviates mTOR inhibitor resistance in triple-negative breast cancer
por: He, Jichao, et al.
Publicado: (2019)

Cortisol inhibits mTOR signaling in avascular necrosis of the femoral head
por: Liao, Yun, et al.
Publicado: (2017)

CPA4 Promotes EMT in Pancreatic Cancer via Stimulating PI3K-AKT-mTOR Signaling
por: Shao, Qingliang, et al.
Publicado: (2020)

ETHE1 Accelerates Triple-Negative Breast Cancer Metastasis by Activating GCN2/eIF2α/ATF4 Signaling
por: Yang, Shao-Ying, et al.
Publicado: (2023)

Decorin Suppresses Invasion and EMT Phenotype of Glioma by Inducing Autophagy via c-Met/Akt/mTOR Axis
por: Jia, Yanfei, et al.
Publicado: (2021)

New Insights into the Role of Exercise in Inhibiting mTOR Signaling in Triple-Negative Breast Cancer
por: Agostini, Deborah, et al.
Publicado: (2018)

Co-targeting EGFR and mTOR with gefitinib and everolimus in triple-negative breast cancer cells
por: El Guerrab, Abderrahim, et al.
Publicado: (2020)

Protein Phosphatase 1 Subunit PPP1R14B Stabilizes STMN1 to Promote Progression and Paclitaxel Resistance in Triple-Negative Breast Cancer
por: Liao, Li, et al.
Publicado: (2023)

IMPA2 polymorphisms and risk of ischemic stroke in a northwest Han Chinese population
por: Ma, Qiaoya, et al.
Publicado: (2016)

Derlin1 functions as an oncogene in cervical cancer via AKT/mTOR signaling pathway
por: Li, Ling, et al.
Publicado: (2019)

IMPA Conference on New Trends in Parameter Identification for Mathematical Models
por: Hofmann, Bernd, et al.
Publicado: (2018)

MNX1-AS1 is a functional oncogene that induces EMT and activates the AKT/mTOR pathway and MNX1 in breast cancer
por: Cheng, Yue, et al.
Publicado: (2019)

GABARAP suppresses EMT and breast cancer progression via the AKT/mTOR signaling pathway
por: Liu, Ying, et al.
Publicado: (2021)

Mitochondrial dysfunction in some triple-negative breast cancer cell lines: role of mTOR pathway and therapeutic potential
por: Pelicano, Hélène, et al.
Publicado: (2014)

mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy
por: Tian, Tian, et al.
Publicado: (2019)

Syndecan-1 as an immunogene in Triple-negative breast cancer: regulation tumor-infiltrating lymphocyte in the tumor microenviroment and EMT by TGFb1/Smad pathway
por: Zhong, Ying, et al.
Publicado: (2023)

Arnicolide D Inhibits Triple Negative Breast Cancer Cell Proliferation by Suppression of Akt/mTOR and STAT3 Signaling Pathways
por: Qu, Zhao, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8q2ibbgk4tv5jgnthhd5408etj