Cargando…
Inhibition of TERC inhibits neural apoptosis and inflammation in spinal cord injury through Akt activation and p-38 inhibition via the miR-34a-5p/XBP-1 axis
This study investigated the function of telomerase RNA component (TERC) in spinal cord injury (SCI). SCI models were established in rats via laminectomy and PC-12 cells were treated with lipopolysaccharide (LPS). TERC and miR-34a-5p expressions in cells and rat spinal cords were detected by quantita...
Autores principales: | Ding, Weiguo, Xu, Weixing, Lu, Di, Sheng, Hongfeng, Xu, Xinwei, Xu, Bin, Zheng, Aote |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883688/ https://www.ncbi.nlm.nih.gov/pubmed/36742154 http://dx.doi.org/10.1515/med-2022-0619 |
Ejemplares similares
-
Genetic and Pharmacological Inhibition of p38α Improves Locomotor Recovery after Spinal Cord Injury
por: Umezawa, Hiroki, et al.
Publicado: (2017) -
Selective inhibition of the p38α MAPK–MK2 axis inhibits inflammatory cues including inflammasome priming signals
por: Wang, Chun, et al.
Publicado: (2018) -
B7-H4 Treatment of T Cells Inhibits ERK, JNK, p38, and AKT Activation
por: Wang, Xiaojie, et al.
Publicado: (2012) -
Ouabain inhibits p38 activation in mice neutrophils
por: Cavalcante‑Silva, Luiz Henrique Agra, et al.
Publicado: (2021) -
Farrerol Relieve Lipopolysaccharide (LPS)-Induced Mastitis by Inhibiting AKT/NF-κB p65, ERK1/2 and P38 Signaling Pathway
por: Li, Yanwei, et al.
Publicado: (2018)