A modular vaccine platform enabled by decoration of bacterial outer membrane vesicles with biotinylated antigens

Engineered outer membrane vesicles (OMVs) derived from Gram-negative bacteria are a promising technology for the creation of non-infectious, nanoparticle vaccines against diverse pathogens. However, antigen display on OMVs can be difficult to control and highly variable due to bottlenecks in protein...

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Detalles Bibliográficos
Autores principales: Weyant, Kevin B., Oloyede, Ayomide, Pal, Sukumar, Liao, Julie, Jesus, Mariela Rivera-De, Jaroentomeechai, Thapakorn, Moeller, Tyler D., Hoang-Phou, Steven, Gilmore, Sean F., Singh, Riya, Pan, Daniel C., Putnam, David, Locher, Christopher, de la Maza, Luis M., Coleman, Matthew A., DeLisa, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883832/
https://www.ncbi.nlm.nih.gov/pubmed/36709333
http://dx.doi.org/10.1038/s41467-023-36101-2

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