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The involvement and therapeutic potential of lncRNA Kcnq1ot1/miR-34a-5p/Sirt1 pathway in arsenic trioxide-induced cardiotoxicity

BACKGROUND/AIMS: Arsenic trioxide (ATO) is the first-line therapeutic drug for acute promyelocytic leukemia. However, the cardiotoxicity of ATO limits its clinical application. This study aims to explore the long noncoding RNA (lncRNA) involved molecular mechanism in ATO-induced cardiotoxicity and t...

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Detalles Bibliográficos
Autores principales:	Shen, Xiuyun, Zhi, Fengnan, Shi, Chunpeng, Xu, Jincheng, Chao, Yuqiu, Xu, Juan, Bai, Yunlong, Jiang, Yanan, Yang, Baofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883885/ https://www.ncbi.nlm.nih.gov/pubmed/36707890 http://dx.doi.org/10.1186/s12967-023-03895-0

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