Mucoadhesive Nanoparticles Enhance the Therapeutic Effect of Dexamethasone on Experimental Ulcerative Colitis by the Local Administration as an Enema

BACKGROUND: As the first-line drug to treat ulcerative colitis (UC), long-term use of glucocorticoids (GCs) produces severe toxic and side effects. Local administration as enema can increase the local GCs concentrations and reduce systemic exposure to high oral doses by directly delivering GCs to th...

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Detalles Bibliográficos
Autores principales: Dong, Kai, Deng, Shu-Jing, He, Bin-Yang, Guo, Zi-Yang, Guan, Ze-Lin, Leng, Xue, Ma, Rui-Rui, Wang, Dan-Yang, Xing, Jian-Feng, You, Cui-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884054/
https://www.ncbi.nlm.nih.gov/pubmed/36718245
http://dx.doi.org/10.2147/DDDT.S390274

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