Hemophagocytic Lymphohistiocytosis Following COVID-19 Infection

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been associated with multiple inflammatory symptoms involving several organ systems, including hematologic manifestations. Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening s...

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Detalles Bibliográficos
Autores principales: Molina, Guarina, Contreras, Rafael, Coombes, Kyle, Walgamage, Thilini, Perozo, Maria A, DesBiens, Martha T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Allergy/Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884115/
https://www.ncbi.nlm.nih.gov/pubmed/36721708
http://dx.doi.org/10.7759/cureus.34307
Descripción
Sumario:Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been associated with multiple inflammatory symptoms involving several organ systems, including hematologic manifestations. Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome caused by excessive inflammation in the absence of immune regulation. We present the case of a patient with HLH secondary to dysregulated inflammatory response following COVID-19; we also describe the diagnostic and management challenges associated with the condition.

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