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Induction of pancreatic neoplasia in the KRAS/TP53 Oncopig

The 5-year survival of pancreatic cancer (PC) remains low. Murine models may not adequately mimic human PC and can be too small for medical device development. A large-animal PC model could address these issues. We induced and characterized pancreatic tumors in Oncopigs (transgenic swine containing...

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Detalles Bibliográficos
Autores principales: Mondal, Pinaki, Patel, Neesha S., Bailey, Katie, Aravind, Shruthishree, Cartwright, Sara B., Hollingsworth, Michael A., Lazenby, Audrey J., Carlson, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884120/
https://www.ncbi.nlm.nih.gov/pubmed/36579622
http://dx.doi.org/10.1242/dmm.049699

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