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Induction of pancreatic neoplasia in the KRAS/TP53 Oncopig
The 5-year survival of pancreatic cancer (PC) remains low. Murine models may not adequately mimic human PC and can be too small for medical device development. A large-animal PC model could address these issues. We induced and characterized pancreatic tumors in Oncopigs (transgenic swine containing...
Autores principales: | Mondal, Pinaki, Patel, Neesha S., Bailey, Katie, Aravind, Shruthishree, Cartwright, Sara B., Hollingsworth, Michael A., Lazenby, Audrey J., Carlson, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884120/ https://www.ncbi.nlm.nih.gov/pubmed/36579622 http://dx.doi.org/10.1242/dmm.049699 |
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