The classical pathway triggers pathogenic complement activation in membranous nephropathy

Membranous nephropathy (MN) is an antibody-mediated autoimmune disease characterized by glomerular immune complexes containing complement components. However, both the initiation pathways and the pathogenic significance of complement activation in MN are poorly understood. Here, we show that compone...

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Detalles Bibliográficos
Autores principales: Seifert, Larissa, Zahner, Gunther, Meyer-Schwesinger, Catherine, Hickstein, Naemi, Dehde, Silke, Wulf, Sonia, Köllner, Sarah M. S., Lucas, Renke, Kylies, Dominik, Froembling, Sarah, Zielinski, Stephanie, Kretz, Oliver, Borodovsky, Anna, Biniaminov, Sergey, Wang, Yanyan, Cheng, Hong, Koch-Nolte, Friedrich, Zipfel, Peter F., Hopfer, Helmut, Puelles, Victor G., Panzer, Ulf, Huber, Tobias B., Wiech, Thorsten, Tomas, Nicola M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884226/
https://www.ncbi.nlm.nih.gov/pubmed/36709213
http://dx.doi.org/10.1038/s41467-023-36068-0

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