Polymeric immunoglobulin receptor deficiency exacerbates autoimmune hepatitis by inducing intestinal dysbiosis and barrier dysfunction

Autoimmune hepatitis (AIH) is an immune-mediated inflammatory liver disease with unclear pathogenesis. The gut microbiota and intestinal barrier play an essential role in AIH. Polymeric immunoglobulin receptor (pIgR) is a central component of mucosal immunity. Herein, we aimed to test the hypothesis...

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Detalles Bibliográficos
Autores principales: Lin, Hongwei, Lin, Jing, Pan, Tongtong, Li, Ting, Jiang, Huimian, Fang, Yan, Wang, Yuxin, Wu, Faling, Huang, Jia, Zhang, Huadong, Chen, Dazhi, Chen, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884241/
https://www.ncbi.nlm.nih.gov/pubmed/36709322
http://dx.doi.org/10.1038/s41419-023-05589-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884241/
https://www.ncbi.nlm.nih.gov/pubmed/36709322
http://dx.doi.org/10.1038/s41419-023-05589-3

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