Intracellular Binding of Terfenadine Competes with Its Access to Pancreatic ß-cell ATP-Sensitive K(+) Channels and Human ether-à-go-go-Related Gene Channels

Most blockers of both hERG (human ether-à-go-go-related gene) channels and pancreatic ß-cell ATP-sensitive K(+) (K(ATP)) channels access their binding sites from the cytoplasmic side of the plasma membrane. It is unknown whether binding to intracellular components competes with binding of these subs...

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Detalles Bibliográficos
Autores principales: Zünkler, Bernd J., Wos-Maganga, Maria, Bohnet, Stefanie, Kleinau, Anne, Manns, Detlef, Chatterjee, Shivani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884252/
https://www.ncbi.nlm.nih.gov/pubmed/35763054
http://dx.doi.org/10.1007/s00232-022-00252-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884252/
https://www.ncbi.nlm.nih.gov/pubmed/35763054
http://dx.doi.org/10.1007/s00232-022-00252-y

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