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Visualizing the Domino-Like Prepore-to-Pore Transition of Streptolysin O by High-Speed AFM
Pore-forming proteins (PFPs) are produced by various organisms, including pathogenic bacteria, and form pores within the target cell membrane. Streptolysin O (SLO) is a PFP produced by Streptococcus pyogenes and forms high-order oligomers on the membrane surface. In this prepore state, multiple α-he...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884259/ https://www.ncbi.nlm.nih.gov/pubmed/35980453 http://dx.doi.org/10.1007/s00232-022-00261-x |