Cargando…

Transcription factor EB regulates phosphatidylinositol-3-phosphate levels that control lysosome positioning in the bladder cancer model

Lysosomes orchestrate degradation and recycling of exogenous and endogenous material thus controlling cellular homeostasis. Little is known how this organelle changes during cancer. Here we investigate the intracellular landscape of lysosomes in a cellular model of bladder cancer. Employing standard...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mathur, Pallavi, De Barros Santos, Camilla, Lachuer, Hugo, Patat, Julie, Latgé, Bruno, Radvanyi, François, Goud, Bruno, Schauer, Kristine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884284/ https://www.ncbi.nlm.nih.gov/pubmed/36709383 http://dx.doi.org/10.1038/s42003-023-04501-1

Ejemplares similares

Spatial organization of lysosomal exocytosis relies on membrane tension gradients
por: Lachuer, Hugo, et al.
Publicado: (2023)

Sequential actions of phosphatidylinositol phosphates regulate phagosome-lysosome fusion
por: Jeschke, Andreas, et al.
Publicado: (2018)

Deregulation of Rab and Rab Effector Genes in Bladder Cancer
por: Ho, Joel R., et al.
Publicado: (2012)

Structural basis for phosphatidylinositol-phosphate biosynthesis
por: Clarke, Oliver B., et al.
Publicado: (2015)

The role of phosphatidylinositol 4-kinases and phosphatidylinositol 4-phosphate during viral replication
por: Delang, Leen, et al.
Publicado: (2012)

Phosphatidylinositol-4-phosphate joins the dance of plant autophagosome formation
por: Gomez, Rodrigo Enrique, et al.
Publicado: (2022)

Phosphatidylinositol-4-Phosphate 5-Kinases and Phosphatidylinositol 4,5-Bisphosphate Synthesis in the Brain
por: Volpicelli-Daley, Laura A., et al.
Publicado: (2010)

Phosphatidylinositol-4-phosphate controls autophagosome formation in Arabidopsis thaliana
por: Gomez, Rodrigo Enrique, et al.
Publicado: (2022)

Structure of Mycobacterium tuberculosis phosphatidylinositol phosphate synthase reveals mechanism of substrate binding and metal catalysis
por: Grāve, Kristīne, et al.
Publicado: (2019)

Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers
por: de Saint-Jean, Maud, et al.
Publicado: (2011)

Exploring phosphatidylinositol 5-phosphate 4-kinase function
por: Bulley, Simon J., et al.
Publicado: (2015)

Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis
por: Levin, Roni, et al.
Publicado: (2017)

The Role of Phosphatidylinositol Phosphate Kinases during Viral Infection
por: Beziau, Anne, et al.
Publicado: (2020)

Amyloid β-Induced Redistribution of Transcriptional Factor EB and Lysosomal Dysfunction in Primary Microglial Cells
por: Guo, Xingzhi, et al.
Publicado: (2017)

Two phosphatidylinositol 4-kinases control lysosomal delivery of the Gaucher disease enzyme, β-glucocerebrosidase
por: Jović, Marko, et al.
Publicado: (2012)

NPC1 regulates the distribution of phosphatidylinositol 4‐kinases at Golgi and lysosomal membranes
por: Kutchukian, Candice, et al.
Publicado: (2021)

Foot-and-mouth disease virus replicates independently of phosphatidylinositol 4-phosphate and type III phosphatidylinositol 4-kinases
por: Berryman, Stephen, et al.
Publicado: (2016)

Suppression of lysosomal acid alpha‐glucosidase impacts the modulation of transcription factor EB translocation in pancreatic cancer
por: Hamura, Ryoga, et al.
Publicado: (2021)

Phosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell Activation
por: Porciello, Nicla, et al.
Publicado: (2016)

VIPP1 rods engulf membranes containing phosphatidylinositol phosphates
por: Theis, Jasmine, et al.
Publicado: (2019)

Design, synthesis and evaluation of a tripodal receptor for phosphatidylinositol phosphates
por: Reeh, Katharina, et al.
Publicado: (2020)

In vitro reconstitution of Sgk3 activation by phosphatidylinositol 3-phosphate
por: Pokorny, Daniel, et al.
Publicado: (2021)

Reinvestigation of carbohydrate specificity of EB-A2 monoclonal antibody used in the immune detection of Aspergillus fumigatus galactomannan
por: Krylov, Vadim B., et al.
Publicado: (2019)

Enhancing lysosomal biogenesis and autophagic flux by activating the transcription factor EB protects against cadmium-induced neurotoxicity
por: Pi, Huifeng, et al.
Publicado: (2017)

Transcription factor EB agonists from natural products for treating human diseases with impaired autophagy-lysosome pathway
por: Xu, Jie, et al.
Publicado: (2020)

Zinc enhances autophagic flux and lysosomal function through transcription factor EB activation and V-ATPase assembly
por: Kim, Ki-Ryeong, et al.
Publicado: (2022)

Sub-lethal oxidative stress induces lysosome biogenesis via a lysosomal membrane permeabilization-cathepsin-caspase 3-transcription factor EB-dependent pathway
por: Leow, San Min, et al.
Publicado: (2016)

Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I α
por: Sasaki, Junko, et al.
Publicado: (2005)

Phosphatidylinositol 5-phosphate is a second messenger important for cell migration
por: Haugsten, Ellen Margrethe, et al.
Publicado: (2013)

Phosphatidylinositol-3-phosphate is light-regulated and essential for survival in retinal rods
por: He, Feng, et al.
Publicado: (2016)

Prevention of Proliferative Vitreoretinopathy by Suppression of Phosphatidylinositol 5-Phosphate 4-Kinases
por: Ma, Gaoen, et al.
Publicado: (2016)

Structural, thermodynamic, and phosphatidylinositol 3‐phosphate binding properties of Phafin2
por: Tang, Tuo‐Xian, et al.
Publicado: (2017)

Increased fatty acyl saturation of phosphatidylinositol phosphates in prostate cancer progression
por: Koizumi, Atsushi, et al.
Publicado: (2019)

Endosomal phosphatidylinositol 3‐phosphate controls synaptic vesicle cycling and neurotransmission
por: Liu, Guan‐Ting, et al.
Publicado: (2022)

An acquired phosphatidylinositol 4-phosphate transport initiates T-cell deterioration and leukemogenesis
por: Zhong, Wenbin, et al.
Publicado: (2022)

Plasma Membrane Phosphatidylinositol 4-Phosphate Is Necessary for Virulence of Candida albicans
por: Konopka, James B.
Publicado: (2022)

Rab5 Isoforms Orchestrate a “Division of Labor” in the Endocytic Network; Rab5C Modulates Rac-Mediated Cell Motility
por: Chen, Pin-I, et al.
Publicado: (2014)

Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells
Publicado: (1995)

Novel insights into the epidemiology of epidermolysis bullosa (EB) from the Dutch EB Registry: EB more common than previously assumed?
por: Baardman, R., et al.
Publicado: (2020)

Activation of Transcription Factor EB Alleviates Tubular Epithelial Cell Injury via Restoring Lysosomal Homeostasis in Diabetic Nephropathy
por: Wang, Shujun, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_n8q0ll0n4ufe4om993v01mbmb7