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Clinical manifestations of COVID-19 in patients with asthma, hypertension, and diabetes mellitus
The clinical symptoms of COVID-19 infection differ from one patient to another, requiring different management. This study intended to characterize the clinical manifestation of COVID-19 in patients with asthma, hypertension, and diabetes mellitus (DM). We analyzed data from 540 medical records of p...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Carol Davila University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884347/ https://www.ncbi.nlm.nih.gov/pubmed/36762324 http://dx.doi.org/10.25122/jml-2021-0364 |
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author | Budiarti, Retno Ediono, Ediono Kalaznykov, Mohammad Yamaoka, Yoshio Miftahussurur, Muhammad |
author_facet | Budiarti, Retno Ediono, Ediono Kalaznykov, Mohammad Yamaoka, Yoshio Miftahussurur, Muhammad |
author_sort | Budiarti, Retno |
collection | PubMed |
description | The clinical symptoms of COVID-19 infection differ from one patient to another, requiring different management. This study intended to characterize the clinical manifestation of COVID-19 in patients with asthma, hypertension, and diabetes mellitus (DM). We analyzed data from 540 medical records of patients with comorbidities like asthma, hypertension, and DM diagnosed with COVID-19, looking at vital signs upon admission, chest X-ray, and laboratory results. Most patients were male (57.0%). The most prevalent comorbidity was hypertension (46.3%) and DM (46.3%), followed by asthma (7.4%). 273 patients had improved condition (50.6%). Patients with hypertension had the most extended length of stay compared to other comorbidities groups (13.0±8.5 days). There were significant differences in the oxygen saturation and respiration rate between the three groups (p=0.002, p<0.0001, respectively). The mean lymphocyte (p=0.028) and hematocrit count (p=0.001) were significantly different between the three comorbid groups, with the hypertension group having the highest mean lymphocyte (15.1±8.9) and hematocrit (38.7±6.9) count. COVID-19 had a significant impact on patients with asthma, hypertension, and diabetes comorbidities concerning the final condition, length of stay, oxygen saturation, and respiratory rate, and also on the hematology level, mainly lymphocyte and hematocrit. Treatment, age, and infection might be determinant factors for different outcomes in each type of comorbidity. |
format | Online Article Text |
id | pubmed-9884347 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Carol Davila University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-98843472023-02-08 Clinical manifestations of COVID-19 in patients with asthma, hypertension, and diabetes mellitus Budiarti, Retno Ediono, Ediono Kalaznykov, Mohammad Yamaoka, Yoshio Miftahussurur, Muhammad J Med Life Original Article The clinical symptoms of COVID-19 infection differ from one patient to another, requiring different management. This study intended to characterize the clinical manifestation of COVID-19 in patients with asthma, hypertension, and diabetes mellitus (DM). We analyzed data from 540 medical records of patients with comorbidities like asthma, hypertension, and DM diagnosed with COVID-19, looking at vital signs upon admission, chest X-ray, and laboratory results. Most patients were male (57.0%). The most prevalent comorbidity was hypertension (46.3%) and DM (46.3%), followed by asthma (7.4%). 273 patients had improved condition (50.6%). Patients with hypertension had the most extended length of stay compared to other comorbidities groups (13.0±8.5 days). There were significant differences in the oxygen saturation and respiration rate between the three groups (p=0.002, p<0.0001, respectively). The mean lymphocyte (p=0.028) and hematocrit count (p=0.001) were significantly different between the three comorbid groups, with the hypertension group having the highest mean lymphocyte (15.1±8.9) and hematocrit (38.7±6.9) count. COVID-19 had a significant impact on patients with asthma, hypertension, and diabetes comorbidities concerning the final condition, length of stay, oxygen saturation, and respiratory rate, and also on the hematology level, mainly lymphocyte and hematocrit. Treatment, age, and infection might be determinant factors for different outcomes in each type of comorbidity. Carol Davila University Press 2022-12 /pmc/articles/PMC9884347/ /pubmed/36762324 http://dx.doi.org/10.25122/jml-2021-0364 Text en ©2022 JOURNAL of MEDICINE and LIFE https://creativecommons.org/licenses/by/3.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ), which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Original Article Budiarti, Retno Ediono, Ediono Kalaznykov, Mohammad Yamaoka, Yoshio Miftahussurur, Muhammad Clinical manifestations of COVID-19 in patients with asthma, hypertension, and diabetes mellitus |
title | Clinical manifestations of COVID-19 in patients with asthma, hypertension, and diabetes mellitus |
title_full | Clinical manifestations of COVID-19 in patients with asthma, hypertension, and diabetes mellitus |
title_fullStr | Clinical manifestations of COVID-19 in patients with asthma, hypertension, and diabetes mellitus |
title_full_unstemmed | Clinical manifestations of COVID-19 in patients with asthma, hypertension, and diabetes mellitus |
title_short | Clinical manifestations of COVID-19 in patients with asthma, hypertension, and diabetes mellitus |
title_sort | clinical manifestations of covid-19 in patients with asthma, hypertension, and diabetes mellitus |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884347/ https://www.ncbi.nlm.nih.gov/pubmed/36762324 http://dx.doi.org/10.25122/jml-2021-0364 |
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