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Leukocytoclastic Vasculitis and Myositis as Initial Manifestations of Crohn’s Disease

Crohn’s disease is a chronic inflammatory condition that mainly affects the digestive tract; however, it possesses extra-intestinal manifestations. We present a case of a 19-year-old male with a history of non-specific gastrointestinal (GI) symptoms of nausea, vomiting, and diarrhea who underwent a...

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Autores principales: Torere, Beatrice E, Aiwuyo, Henry O, Kennard, Jennifer L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884403/
https://www.ncbi.nlm.nih.gov/pubmed/36721609
http://dx.doi.org/10.7759/cureus.33127
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author Torere, Beatrice E
Aiwuyo, Henry O
Kennard, Jennifer L
author_facet Torere, Beatrice E
Aiwuyo, Henry O
Kennard, Jennifer L
author_sort Torere, Beatrice E
collection PubMed
description Crohn’s disease is a chronic inflammatory condition that mainly affects the digestive tract; however, it possesses extra-intestinal manifestations. We present a case of a 19-year-old male with a history of non-specific gastrointestinal (GI) symptoms of nausea, vomiting, and diarrhea who underwent a colonoscopy with a biopsy due to worsening GI symptoms. The colonoscopy was inconclusive for GI pathology. Three months later, he developed several symptoms, which were later indicative of leukocytoclastic vasculitis and myositis as extra-intestinal manifestations of Crohn’s disease. The patient was started on high-dose prednisolone, which improved his symptoms remarkably, and the steroid dose was tapered gradually. He was subsequently followed up by the Rheumatology and Gastroenterology outpatient departments. The case reinforces the need for physicians to have a high index of suspicion in patients with non-specific GI symptoms presenting with new-onset cutaneous manifestations and myositis.
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spelling pubmed-98844032023-01-30 Leukocytoclastic Vasculitis and Myositis as Initial Manifestations of Crohn’s Disease Torere, Beatrice E Aiwuyo, Henry O Kennard, Jennifer L Cureus Internal Medicine Crohn’s disease is a chronic inflammatory condition that mainly affects the digestive tract; however, it possesses extra-intestinal manifestations. We present a case of a 19-year-old male with a history of non-specific gastrointestinal (GI) symptoms of nausea, vomiting, and diarrhea who underwent a colonoscopy with a biopsy due to worsening GI symptoms. The colonoscopy was inconclusive for GI pathology. Three months later, he developed several symptoms, which were later indicative of leukocytoclastic vasculitis and myositis as extra-intestinal manifestations of Crohn’s disease. The patient was started on high-dose prednisolone, which improved his symptoms remarkably, and the steroid dose was tapered gradually. He was subsequently followed up by the Rheumatology and Gastroenterology outpatient departments. The case reinforces the need for physicians to have a high index of suspicion in patients with non-specific GI symptoms presenting with new-onset cutaneous manifestations and myositis. Cureus 2022-12-30 /pmc/articles/PMC9884403/ /pubmed/36721609 http://dx.doi.org/10.7759/cureus.33127 Text en Copyright © 2022, Torere et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Torere, Beatrice E
Aiwuyo, Henry O
Kennard, Jennifer L
Leukocytoclastic Vasculitis and Myositis as Initial Manifestations of Crohn’s Disease
title Leukocytoclastic Vasculitis and Myositis as Initial Manifestations of Crohn’s Disease
title_full Leukocytoclastic Vasculitis and Myositis as Initial Manifestations of Crohn’s Disease
title_fullStr Leukocytoclastic Vasculitis and Myositis as Initial Manifestations of Crohn’s Disease
title_full_unstemmed Leukocytoclastic Vasculitis and Myositis as Initial Manifestations of Crohn’s Disease
title_short Leukocytoclastic Vasculitis and Myositis as Initial Manifestations of Crohn’s Disease
title_sort leukocytoclastic vasculitis and myositis as initial manifestations of crohn’s disease
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884403/
https://www.ncbi.nlm.nih.gov/pubmed/36721609
http://dx.doi.org/10.7759/cureus.33127
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