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GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes

In the mammalian central nervous system (CNS), astrocytes are indispensable for brain development, function, and health. However, non-invasive tools to study astrocyte biology and function in vivo have been limited to genetically modified mice. CRISPR/Cas9-based genome engineering enables rapid and...

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Detalles Bibliográficos
Autores principales:	Bindu, Dhanesh Sivadasan, Tan, Christabel Xin, Savage, Justin T., Eroglu, Cagla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884502/ https://www.ncbi.nlm.nih.gov/pubmed/36711516 http://dx.doi.org/10.1101/2023.01.17.524433

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