Myosin-binding protein C stabilizes, but is not the sole determinant of SRX myosin in cardiac muscle

The myosin super-relaxed (SRX) state is central to striated muscle metabolic and functional regulation. In skeletal muscle, SRX myosin are predominantly colocalized with myosin-binding protein C (MyBP-C) in the sarcomere C-zone. To define how cardiac MyBP-C (cMyBP-C) and its specific domains contrib...

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Detalles Bibliográficos
Autores principales: Nelson, Shane, Beck-Previs, Samantha, Sadayappan, Sakthivel, Tong, Carl, Warshaw, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884578/
https://www.ncbi.nlm.nih.gov/pubmed/36688870
http://dx.doi.org/10.1085/jgp.202213276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884578/
https://www.ncbi.nlm.nih.gov/pubmed/36688870
http://dx.doi.org/10.1085/jgp.202213276

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