Mismatch repair is a double-edged sword in the battle against microsatellite instability

Roughly 3% of the human genome consists of microsatellites or tracts of short tandem repeats (STRs). These STRs are often unstable, undergoing high-frequency expansions (increases) or contractions (decreases) in the number of repeat units. Some microsatellite instability (MSI) is seen at multiple ST...

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Detalles Bibliográficos
Autores principales: Miller, Carson J., Usdin, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884765/
https://www.ncbi.nlm.nih.gov/pubmed/36059110
http://dx.doi.org/10.1017/erm.2022.16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884765/
https://www.ncbi.nlm.nih.gov/pubmed/36059110
http://dx.doi.org/10.1017/erm.2022.16

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