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Increased HIV‐1 infection in PBMCs treated in vitro with menstrual cycle phase hormones or medroxyprogesterone acetate likely occurs via different mechanisms

PROBLEM: Both luteal phase progesterone (P4) levels and use of the intramuscular (IM) injectable progestin‐only contraceptive depo‐medroxyprogesterone acetate (DMPA‐IM) have been linked to increased S/HIV acquisition in animal, clinical and in vitro models. Several plausible mechanisms could explain...

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Detalles Bibliográficos
Autores principales: Bick, Alexis J., Avenant, Chanel, Tomasicchio, Michele, van der Spuy, Zephne, Hapgood, Janet P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884997/
https://www.ncbi.nlm.nih.gov/pubmed/36302121
http://dx.doi.org/10.1111/aji.13643

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