Different sea urchin RAG-like genes were domesticated to carry out different functions

The closely linked recombination activating genes (RAG1 and RAG2) in vertebrates encode the core of the RAG recombinase that mediates the V(D)J recombination of the immunoglobulin and T-cell receptor genes. RAG1 and RAG2 homologues (RAG1L and RAG2L) are present in multiple invertebrate phyla, includ...

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Detalles Bibliográficos
Autores principales: Yakovenko, Iryna, Tobi, Dror, Ner-Gaon, Hadas, Oren, Matan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885083/
https://www.ncbi.nlm.nih.gov/pubmed/36726993
http://dx.doi.org/10.3389/fimmu.2022.1066510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885083/
https://www.ncbi.nlm.nih.gov/pubmed/36726993
http://dx.doi.org/10.3389/fimmu.2022.1066510

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