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Impact of SIV infection on mycobacterial lipid-reactive T cell responses in Bacillus Calmette-Guérin (BCG) inoculated macaques

BACKGROUND: Although BCG vaccine protects infants from tuberculosis (TB), it has limited efficacy in adults against pulmonary TB. Further, HIV coinfection significantly increases the risk of developing active TB. In the lack of defined correlates of protection in TB disease, it is essential to explo...

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Detalles Bibliográficos
Autores principales: Walker, Edith M., Merino, Kristen M., Slisarenko, Nadia, Grasperge, Brooke F., Mehra, Smriti, Roy, Chad J., Kaushal, Deepak, Rout, Namita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885173/
https://www.ncbi.nlm.nih.gov/pubmed/36726992
http://dx.doi.org/10.3389/fimmu.2022.1085786