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Predictors of recurrence in patients without non‐inducibility of ventricular tachycardia at the end of ablation

BACKGROUND: Ventricular tachycardia (VT) non‐inducibility at the end of ablation is associated with a less likely VT recurrence. However, it is not clear whether we should use VT non‐inducibility as a routine end point of VT ablation. The aim of this study was to evaluate VT recurrence in patients i...

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Autores principales: Nakasone, Kazutaka, Fukuzawa, Koji, Kiuchi, Kunihiko, Takami, Mitsuru, Sakai, Jun, Nakamura, Toshihiro, Yatomi, Atsusuke, Sonoda, Yusuke, Takahara, Hiroyuki, Yamamoto, Kyoko, Suzuki, Yuya, Tani, Ken‐ichi, Iwai, Hidehiro, Nakanishi, Yusuke, Hirata, Ken‐ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885314/
https://www.ncbi.nlm.nih.gov/pubmed/36733320
http://dx.doi.org/10.1002/joa3.12796
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author Nakasone, Kazutaka
Fukuzawa, Koji
Kiuchi, Kunihiko
Takami, Mitsuru
Sakai, Jun
Nakamura, Toshihiro
Yatomi, Atsusuke
Sonoda, Yusuke
Takahara, Hiroyuki
Yamamoto, Kyoko
Suzuki, Yuya
Tani, Ken‐ichi
Iwai, Hidehiro
Nakanishi, Yusuke
Hirata, Ken‐ichi
author_facet Nakasone, Kazutaka
Fukuzawa, Koji
Kiuchi, Kunihiko
Takami, Mitsuru
Sakai, Jun
Nakamura, Toshihiro
Yatomi, Atsusuke
Sonoda, Yusuke
Takahara, Hiroyuki
Yamamoto, Kyoko
Suzuki, Yuya
Tani, Ken‐ichi
Iwai, Hidehiro
Nakanishi, Yusuke
Hirata, Ken‐ichi
author_sort Nakasone, Kazutaka
collection PubMed
description BACKGROUND: Ventricular tachycardia (VT) non‐inducibility at the end of ablation is associated with a less likely VT recurrence. However, it is not clear whether we should use VT non‐inducibility as a routine end point of VT ablation. The aim of this study was to evaluate VT recurrence in patients in whom VT non‐inducibility was not achieved at the end of the radiofrequency (RF) ablation and the factors attributing to the VT recurrence. METHODS: We analyzed that 62 patients in whom VT non‐inducibility was not achieved at the end of the RF ablation were studied. RESULTS: Over 2 years, 22 (35%) of the cases had VT recurrences. A multivariate analysis showed that an LVEF ≥35% (HR: 0.19; 95% CI: 0.06–0.49; p < .01) and elimination of the clinical VT as an acute ablation efficacy (HR: 0.23; 95% CI: 0.04–0.81; p = .02) were independent predictors of fewer VT recurrences. RF ablation was associated with a 91.1% reduction in VT episodes. CONCLUSION: Even if VT non‐inducibility was not achieved, patients with an LVEF ≥35% or in whom the clinical VT could be eliminated might be prevented from having VT recurrences. The validity of the VT non‐inducibility of any VT should be evaluated considering each patient's background and the results of the procedure.
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spelling pubmed-98853142023-02-01 Predictors of recurrence in patients without non‐inducibility of ventricular tachycardia at the end of ablation Nakasone, Kazutaka Fukuzawa, Koji Kiuchi, Kunihiko Takami, Mitsuru Sakai, Jun Nakamura, Toshihiro Yatomi, Atsusuke Sonoda, Yusuke Takahara, Hiroyuki Yamamoto, Kyoko Suzuki, Yuya Tani, Ken‐ichi Iwai, Hidehiro Nakanishi, Yusuke Hirata, Ken‐ichi J Arrhythm Original Articles BACKGROUND: Ventricular tachycardia (VT) non‐inducibility at the end of ablation is associated with a less likely VT recurrence. However, it is not clear whether we should use VT non‐inducibility as a routine end point of VT ablation. The aim of this study was to evaluate VT recurrence in patients in whom VT non‐inducibility was not achieved at the end of the radiofrequency (RF) ablation and the factors attributing to the VT recurrence. METHODS: We analyzed that 62 patients in whom VT non‐inducibility was not achieved at the end of the RF ablation were studied. RESULTS: Over 2 years, 22 (35%) of the cases had VT recurrences. A multivariate analysis showed that an LVEF ≥35% (HR: 0.19; 95% CI: 0.06–0.49; p < .01) and elimination of the clinical VT as an acute ablation efficacy (HR: 0.23; 95% CI: 0.04–0.81; p = .02) were independent predictors of fewer VT recurrences. RF ablation was associated with a 91.1% reduction in VT episodes. CONCLUSION: Even if VT non‐inducibility was not achieved, patients with an LVEF ≥35% or in whom the clinical VT could be eliminated might be prevented from having VT recurrences. The validity of the VT non‐inducibility of any VT should be evaluated considering each patient's background and the results of the procedure. John Wiley and Sons Inc. 2022-11-15 /pmc/articles/PMC9885314/ /pubmed/36733320 http://dx.doi.org/10.1002/joa3.12796 Text en © 2022 The Authors. Journal of Arrhythmia published by John Wiley & Sons Australia, Ltd on behalf of Japanese Heart Rhythm Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Nakasone, Kazutaka
Fukuzawa, Koji
Kiuchi, Kunihiko
Takami, Mitsuru
Sakai, Jun
Nakamura, Toshihiro
Yatomi, Atsusuke
Sonoda, Yusuke
Takahara, Hiroyuki
Yamamoto, Kyoko
Suzuki, Yuya
Tani, Ken‐ichi
Iwai, Hidehiro
Nakanishi, Yusuke
Hirata, Ken‐ichi
Predictors of recurrence in patients without non‐inducibility of ventricular tachycardia at the end of ablation
title Predictors of recurrence in patients without non‐inducibility of ventricular tachycardia at the end of ablation
title_full Predictors of recurrence in patients without non‐inducibility of ventricular tachycardia at the end of ablation
title_fullStr Predictors of recurrence in patients without non‐inducibility of ventricular tachycardia at the end of ablation
title_full_unstemmed Predictors of recurrence in patients without non‐inducibility of ventricular tachycardia at the end of ablation
title_short Predictors of recurrence in patients without non‐inducibility of ventricular tachycardia at the end of ablation
title_sort predictors of recurrence in patients without non‐inducibility of ventricular tachycardia at the end of ablation
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885314/
https://www.ncbi.nlm.nih.gov/pubmed/36733320
http://dx.doi.org/10.1002/joa3.12796
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