AWOT and CWOT for genotype and genotype-by-treatment interaction joint analysis in pharmacogenetics GWAS

MOTIVATION: Pharmacogenomics (PGx) research holds the promise for detecting association between genetic variants and drug responses in randomized clinical trials, but it is limited by small populations and thus has low power to detect signals. It is critical to increase the power of PGx genome-wide...

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Detalles Bibliográficos
Autores principales: Zhang, Hong, Mehrotra, Devan V, Shen, Judong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885423/
https://www.ncbi.nlm.nih.gov/pubmed/36661328
http://dx.doi.org/10.1093/bioinformatics/btac834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885423/
https://www.ncbi.nlm.nih.gov/pubmed/36661328
http://dx.doi.org/10.1093/bioinformatics/btac834

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