Skeletal diseases caused by mutations in PTH1R show aberrant differentiation of skeletal progenitors due to dysregulation of DEPTOR

Alterations in the balance between skeletogenesis and adipogenesis is a pathogenic feature in multiple skeletal disorders. Clinically, enhanced bone marrow adiposity in bones impairs mobility and increases fracture risk, reducing the quality of life of patients. The molecular mechanism that underlie...

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Detalles Bibliográficos
Autores principales: Csukasi, Fabiana, Bosakova, Michaela, Barta, Tomas, Martin, Jorge H., Arcedo, Jesus, Barad, Maya, Rico-Llanos, Gustavo A., Zieba, Jennifer, Becerra, Jose, Krejci, Pavel, Duran, Ivan, Krakow, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885499/
https://www.ncbi.nlm.nih.gov/pubmed/36726589
http://dx.doi.org/10.3389/fcell.2022.963389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885499/
https://www.ncbi.nlm.nih.gov/pubmed/36726589
http://dx.doi.org/10.3389/fcell.2022.963389

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