Presenilins regulate synaptic plasticity in the perforant pathways of the hippocampus

Mutations in the Presenilin genes (PSEN1 and PSEN2) are the major cause of familial Alzheimer’s disease (AD), highlighting the importance of Presenilin (PS) in AD pathogenesis. Previous studies of PS function in the hippocampus demonstrated that loss of PS results in the impairment of short- and lon...

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Detalles Bibliográficos
Autores principales: Lee, Sang Hun, Bolshakov, Vadim Y., Shen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885562/
https://www.ncbi.nlm.nih.gov/pubmed/36710361
http://dx.doi.org/10.1186/s13041-023-01009-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885562/
https://www.ncbi.nlm.nih.gov/pubmed/36710361
http://dx.doi.org/10.1186/s13041-023-01009-x

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