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Convolutional neural network for detecting rib fractures on chest radiographs: a feasibility study

BACKGROUND: Chest radiography is the standard investigation for identifying rib fractures. The application of artificial intelligence (AI) for detecting rib fractures on chest radiographs is limited by image quality control and multilesion screening. To our knowledge, few studies have developed and...

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Autores principales: Wu, Jiangfen, Liu, Nijun, Li, Xianjun, Fan, Qianrui, Li, Zhihao, Shang, Jin, Wang, Fei, Chen, Bowei, Shen, Yuanwang, Cao, Pan, Liu, Zhe, Li, Miaoling, Qian, Jiayao, Yang, Jian, Sun, Qinli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885575/
https://www.ncbi.nlm.nih.gov/pubmed/36717773
http://dx.doi.org/10.1186/s12880-023-00975-x
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author Wu, Jiangfen
Liu, Nijun
Li, Xianjun
Fan, Qianrui
Li, Zhihao
Shang, Jin
Wang, Fei
Chen, Bowei
Shen, Yuanwang
Cao, Pan
Liu, Zhe
Li, Miaoling
Qian, Jiayao
Yang, Jian
Sun, Qinli
author_facet Wu, Jiangfen
Liu, Nijun
Li, Xianjun
Fan, Qianrui
Li, Zhihao
Shang, Jin
Wang, Fei
Chen, Bowei
Shen, Yuanwang
Cao, Pan
Liu, Zhe
Li, Miaoling
Qian, Jiayao
Yang, Jian
Sun, Qinli
author_sort Wu, Jiangfen
collection PubMed
description BACKGROUND: Chest radiography is the standard investigation for identifying rib fractures. The application of artificial intelligence (AI) for detecting rib fractures on chest radiographs is limited by image quality control and multilesion screening. To our knowledge, few studies have developed and verified the performance of an AI model for detecting rib fractures by using multi-center radiographs. And existing studies using chest radiographs for multiple rib fracture detection have used more complex and slower detection algorithms, so we aimed to create a multiple rib fracture detection model by using a convolutional neural network (CNN), based on multi-center and quality-normalised chest radiographs. METHODS: A total of 1080 radiographs with rib fractures were obtained and randomly divided into the training set (918 radiographs, 85%) and the testing set (162 radiographs, 15%). An object detection CNN, You Only Look Once v3 (YOLOv3), was adopted to build the detection model. Receiver operating characteristic (ROC) and free-response ROC (FROC) were used to evaluate the model’s performance. A joint testing group of 162 radiographs with rib fractures and 233 radiographs without rib fractures was used as the internal testing set. Furthermore, an additional 201 radiographs, 121 with rib fractures and 80 without rib fractures, were independently validated to compare the CNN model performance with the diagnostic efficiency of radiologists. RESULTS: The sensitivity of the model in the training and testing sets was 92.0% and 91.1%, respectively, and the precision was 68.0% and 81.6%, respectively. FROC in the testing set showed that the sensitivity for whole-lesion detection reached 91.3% when the false-positive of each case was 0.56. In the joint testing group, the case-level accuracy, sensitivity, specificity, and area under the curve were 85.1%, 93.2%, 79.4%, and 0.92, respectively. At the fracture level and the case level in the independent validation set, the accuracy and sensitivity of the CNN model were always higher or close to radiologists’ readings. CONCLUSIONS: The CNN model, based on YOLOv3, was sensitive for detecting rib fractures on chest radiographs and showed great potential in the preliminary screening of rib fractures, which indicated that CNN can help reduce missed diagnoses and relieve radiologists’ workload. In this study, we developed and verified the performance of a novel CNN model for rib fracture detection by using radiography.
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spelling pubmed-98855752023-01-31 Convolutional neural network for detecting rib fractures on chest radiographs: a feasibility study Wu, Jiangfen Liu, Nijun Li, Xianjun Fan, Qianrui Li, Zhihao Shang, Jin Wang, Fei Chen, Bowei Shen, Yuanwang Cao, Pan Liu, Zhe Li, Miaoling Qian, Jiayao Yang, Jian Sun, Qinli BMC Med Imaging Research BACKGROUND: Chest radiography is the standard investigation for identifying rib fractures. The application of artificial intelligence (AI) for detecting rib fractures on chest radiographs is limited by image quality control and multilesion screening. To our knowledge, few studies have developed and verified the performance of an AI model for detecting rib fractures by using multi-center radiographs. And existing studies using chest radiographs for multiple rib fracture detection have used more complex and slower detection algorithms, so we aimed to create a multiple rib fracture detection model by using a convolutional neural network (CNN), based on multi-center and quality-normalised chest radiographs. METHODS: A total of 1080 radiographs with rib fractures were obtained and randomly divided into the training set (918 radiographs, 85%) and the testing set (162 radiographs, 15%). An object detection CNN, You Only Look Once v3 (YOLOv3), was adopted to build the detection model. Receiver operating characteristic (ROC) and free-response ROC (FROC) were used to evaluate the model’s performance. A joint testing group of 162 radiographs with rib fractures and 233 radiographs without rib fractures was used as the internal testing set. Furthermore, an additional 201 radiographs, 121 with rib fractures and 80 without rib fractures, were independently validated to compare the CNN model performance with the diagnostic efficiency of radiologists. RESULTS: The sensitivity of the model in the training and testing sets was 92.0% and 91.1%, respectively, and the precision was 68.0% and 81.6%, respectively. FROC in the testing set showed that the sensitivity for whole-lesion detection reached 91.3% when the false-positive of each case was 0.56. In the joint testing group, the case-level accuracy, sensitivity, specificity, and area under the curve were 85.1%, 93.2%, 79.4%, and 0.92, respectively. At the fracture level and the case level in the independent validation set, the accuracy and sensitivity of the CNN model were always higher or close to radiologists’ readings. CONCLUSIONS: The CNN model, based on YOLOv3, was sensitive for detecting rib fractures on chest radiographs and showed great potential in the preliminary screening of rib fractures, which indicated that CNN can help reduce missed diagnoses and relieve radiologists’ workload. In this study, we developed and verified the performance of a novel CNN model for rib fracture detection by using radiography. BioMed Central 2023-01-30 /pmc/articles/PMC9885575/ /pubmed/36717773 http://dx.doi.org/10.1186/s12880-023-00975-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Wu, Jiangfen
Liu, Nijun
Li, Xianjun
Fan, Qianrui
Li, Zhihao
Shang, Jin
Wang, Fei
Chen, Bowei
Shen, Yuanwang
Cao, Pan
Liu, Zhe
Li, Miaoling
Qian, Jiayao
Yang, Jian
Sun, Qinli
Convolutional neural network for detecting rib fractures on chest radiographs: a feasibility study
title Convolutional neural network for detecting rib fractures on chest radiographs: a feasibility study
title_full Convolutional neural network for detecting rib fractures on chest radiographs: a feasibility study
title_fullStr Convolutional neural network for detecting rib fractures on chest radiographs: a feasibility study
title_full_unstemmed Convolutional neural network for detecting rib fractures on chest radiographs: a feasibility study
title_short Convolutional neural network for detecting rib fractures on chest radiographs: a feasibility study
title_sort convolutional neural network for detecting rib fractures on chest radiographs: a feasibility study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885575/
https://www.ncbi.nlm.nih.gov/pubmed/36717773
http://dx.doi.org/10.1186/s12880-023-00975-x
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