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Semaphorin 7A interacts with nuclear factor NF-kappa-B p105 via integrin β1 and mediates inflammation

Semaphorin7a (SEMA7A), a membrane-anchored member of the semaphorin protein family, could be involved in a diverse range of immune responses via its receptor integrin β1. Recently, we reported that the SEMA7A(R148W) mutation (a gain-of-function mutation, Sema7a(R145W) in mice) is a risk factor for p...

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Detalles Bibliográficos
Autores principales: Li, Xuan, Xie, Wanlu, Pan, Qiong, Zhang, Xiaoxun, Zhang, Liangjun, Zhao, Nan, Xie, Qiaoling, Ding, Jingjing, Chai, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885601/
https://www.ncbi.nlm.nih.gov/pubmed/36717921
http://dx.doi.org/10.1186/s12964-022-01024-w