Stop GnRH-agonist/GnRH-antagonist protocol: a different insight on ovarian stimulation for IVF

Ovarian stimulation (OS) is one of the key factors in the success of in vitro fertilization-embryo transfer (IVF-ET), by enabling the recruitment of numerous healthy fertilizable oocytes and, thereby, multiple embryos. The Stop GnRH-agonist/GnRH-antagonist (GnRH-ag/GnRH-ant), which offers all the ad...

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Autor principal: Orvieto, Raoul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885692/
https://www.ncbi.nlm.nih.gov/pubmed/36710334
http://dx.doi.org/10.1186/s12958-023-01069-7
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author Orvieto, Raoul
author_facet Orvieto, Raoul
author_sort Orvieto, Raoul
collection PubMed
description Ovarian stimulation (OS) is one of the key factors in the success of in vitro fertilization-embryo transfer (IVF-ET), by enabling the recruitment of numerous healthy fertilizable oocytes and, thereby, multiple embryos. The Stop GnRH-agonist/GnRH-antagonist (GnRH-ag/GnRH-ant), which offers all the advantages of using long suppressive GnRH-ag, with GnRH-ant, is in my opinion a valuable addition to the armamentarium of OS protocols. It allows cycle programming, better follicular synchronization and offers successful outcome in a variety of challenging cases such as poor responders, Poseidon group 4 poor prognosis patients, those with elevated peak progesterone (P) serum levels, poor embryo quality or repeated IVF failures.
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spelling pubmed-98856922023-01-31 Stop GnRH-agonist/GnRH-antagonist protocol: a different insight on ovarian stimulation for IVF Orvieto, Raoul Reprod Biol Endocrinol Review Ovarian stimulation (OS) is one of the key factors in the success of in vitro fertilization-embryo transfer (IVF-ET), by enabling the recruitment of numerous healthy fertilizable oocytes and, thereby, multiple embryos. The Stop GnRH-agonist/GnRH-antagonist (GnRH-ag/GnRH-ant), which offers all the advantages of using long suppressive GnRH-ag, with GnRH-ant, is in my opinion a valuable addition to the armamentarium of OS protocols. It allows cycle programming, better follicular synchronization and offers successful outcome in a variety of challenging cases such as poor responders, Poseidon group 4 poor prognosis patients, those with elevated peak progesterone (P) serum levels, poor embryo quality or repeated IVF failures. BioMed Central 2023-01-30 /pmc/articles/PMC9885692/ /pubmed/36710334 http://dx.doi.org/10.1186/s12958-023-01069-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Orvieto, Raoul
Stop GnRH-agonist/GnRH-antagonist protocol: a different insight on ovarian stimulation for IVF
title Stop GnRH-agonist/GnRH-antagonist protocol: a different insight on ovarian stimulation for IVF
title_full Stop GnRH-agonist/GnRH-antagonist protocol: a different insight on ovarian stimulation for IVF
title_fullStr Stop GnRH-agonist/GnRH-antagonist protocol: a different insight on ovarian stimulation for IVF
title_full_unstemmed Stop GnRH-agonist/GnRH-antagonist protocol: a different insight on ovarian stimulation for IVF
title_short Stop GnRH-agonist/GnRH-antagonist protocol: a different insight on ovarian stimulation for IVF
title_sort stop gnrh-agonist/gnrh-antagonist protocol: a different insight on ovarian stimulation for ivf
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885692/
https://www.ncbi.nlm.nih.gov/pubmed/36710334
http://dx.doi.org/10.1186/s12958-023-01069-7
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