Inhibition of 2-arachidonoylglycerol degradation enhances glial immunity by single-cell transcriptomic analysis

BACKGROUND: 2-Arachidonoylglycerol (2-AG) is the most abundant endogenous cannabinoid. Inhibition of 2-AG metabolism by inactivation of monoacylglycerol lipase (MAGL), the primary enzyme that degrades 2-AG in the brain, produces anti-inflammatory and neuroprotective effects in neurodegenerative dise...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Dexiao, Zhang, Jian, Hashem, Jack, Gao, Fei, Chen, Chu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885699/
https://www.ncbi.nlm.nih.gov/pubmed/36717883
http://dx.doi.org/10.1186/s12974-023-02701-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885699/
https://www.ncbi.nlm.nih.gov/pubmed/36717883
http://dx.doi.org/10.1186/s12974-023-02701-4

Ejemplares similares