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Can the genes communicate with each other after birth? An international cross‐sectional study
BACKGROUND: Various factors contribute to the pathogenesis of a disease. These include genetic factors, family history, and some idiopathic causes. Genetic makeup has an important role in the progression of disease. This is due to mutations in genetic material, that is, deoxyribonucleic acid (DNA)....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885756/ https://www.ncbi.nlm.nih.gov/pubmed/36733667 http://dx.doi.org/10.1002/hsr2.1084 |
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author | Hashim, Hashim Talib Hashim, Ali Talib Nazir, Abubakar Afzaal, Usama Nazir, Awais Al‐Obaidi, Ahmed Dheyaa |
author_facet | Hashim, Hashim Talib Hashim, Ali Talib Nazir, Abubakar Afzaal, Usama Nazir, Awais Al‐Obaidi, Ahmed Dheyaa |
author_sort | Hashim, Hashim Talib |
collection | PubMed |
description | BACKGROUND: Various factors contribute to the pathogenesis of a disease. These include genetic factors, family history, and some idiopathic causes. Genetic makeup has an important role in the progression of disease. This is due to mutations in genetic material, that is, deoxyribonucleic acid (DNA). METHODOLOGY: This is a cross‐sectional study that involved 5000 participants distributed across 250 countries. All the participants were randomly selected and asked to fill out the online survey. All the participants were fully informed about the study's purpose before providing their consent. RESULTS: The participants were distributed among 250 countries. Their age mean (standard deviation) is 46.7 (12.4). We discovered a significant difference between those who have genetic or congenital diseases and those who have a family history of the disease. Also, there is a statistically significant difference between the recurrence of the disease and the duration of the visits of close relatives who have the same disease. CONCLUSION: The study suggests that there might be some ways, through gene waves or the environment, in which a gene changes the expression of other genes of similar sequence in different individuals when the required period of contact is provided. In the future, this theory might explain the idiopathic nature of some diseases. |
format | Online Article Text |
id | pubmed-9885756 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-98857562023-02-01 Can the genes communicate with each other after birth? An international cross‐sectional study Hashim, Hashim Talib Hashim, Ali Talib Nazir, Abubakar Afzaal, Usama Nazir, Awais Al‐Obaidi, Ahmed Dheyaa Health Sci Rep Original Research BACKGROUND: Various factors contribute to the pathogenesis of a disease. These include genetic factors, family history, and some idiopathic causes. Genetic makeup has an important role in the progression of disease. This is due to mutations in genetic material, that is, deoxyribonucleic acid (DNA). METHODOLOGY: This is a cross‐sectional study that involved 5000 participants distributed across 250 countries. All the participants were randomly selected and asked to fill out the online survey. All the participants were fully informed about the study's purpose before providing their consent. RESULTS: The participants were distributed among 250 countries. Their age mean (standard deviation) is 46.7 (12.4). We discovered a significant difference between those who have genetic or congenital diseases and those who have a family history of the disease. Also, there is a statistically significant difference between the recurrence of the disease and the duration of the visits of close relatives who have the same disease. CONCLUSION: The study suggests that there might be some ways, through gene waves or the environment, in which a gene changes the expression of other genes of similar sequence in different individuals when the required period of contact is provided. In the future, this theory might explain the idiopathic nature of some diseases. John Wiley and Sons Inc. 2023-01-30 /pmc/articles/PMC9885756/ /pubmed/36733667 http://dx.doi.org/10.1002/hsr2.1084 Text en © 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Hashim, Hashim Talib Hashim, Ali Talib Nazir, Abubakar Afzaal, Usama Nazir, Awais Al‐Obaidi, Ahmed Dheyaa Can the genes communicate with each other after birth? An international cross‐sectional study |
title | Can the genes communicate with each other after birth? An international cross‐sectional study |
title_full | Can the genes communicate with each other after birth? An international cross‐sectional study |
title_fullStr | Can the genes communicate with each other after birth? An international cross‐sectional study |
title_full_unstemmed | Can the genes communicate with each other after birth? An international cross‐sectional study |
title_short | Can the genes communicate with each other after birth? An international cross‐sectional study |
title_sort | can the genes communicate with each other after birth? an international cross‐sectional study |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885756/ https://www.ncbi.nlm.nih.gov/pubmed/36733667 http://dx.doi.org/10.1002/hsr2.1084 |
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