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Can the genes communicate with each other after birth? An international cross‐sectional study

BACKGROUND: Various factors contribute to the pathogenesis of a disease. These include genetic factors, family history, and some idiopathic causes. Genetic makeup has an important role in the progression of disease. This is due to mutations in genetic material, that is, deoxyribonucleic acid (DNA)....

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Autores principales: Hashim, Hashim Talib, Hashim, Ali Talib, Nazir, Abubakar, Afzaal, Usama, Nazir, Awais, Al‐Obaidi, Ahmed Dheyaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885756/
https://www.ncbi.nlm.nih.gov/pubmed/36733667
http://dx.doi.org/10.1002/hsr2.1084
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author Hashim, Hashim Talib
Hashim, Ali Talib
Nazir, Abubakar
Afzaal, Usama
Nazir, Awais
Al‐Obaidi, Ahmed Dheyaa
author_facet Hashim, Hashim Talib
Hashim, Ali Talib
Nazir, Abubakar
Afzaal, Usama
Nazir, Awais
Al‐Obaidi, Ahmed Dheyaa
author_sort Hashim, Hashim Talib
collection PubMed
description BACKGROUND: Various factors contribute to the pathogenesis of a disease. These include genetic factors, family history, and some idiopathic causes. Genetic makeup has an important role in the progression of disease. This is due to mutations in genetic material, that is, deoxyribonucleic acid (DNA). METHODOLOGY: This is a cross‐sectional study that involved 5000 participants distributed across 250 countries. All the participants were randomly selected and asked to fill out the online survey. All the participants were fully informed about the study's purpose before providing their consent. RESULTS: The participants were distributed among 250 countries. Their age mean (standard deviation) is 46.7 (12.4). We discovered a significant difference between those who have genetic or congenital diseases and those who have a family history of the disease. Also, there is a statistically significant difference between the recurrence of the disease and the duration of the visits of close relatives who have the same disease. CONCLUSION: The study suggests that there might be some ways, through gene waves or the environment, in which a gene changes the expression of other genes of similar sequence in different individuals when the required period of contact is provided. In the future, this theory might explain the idiopathic nature of some diseases.
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spelling pubmed-98857562023-02-01 Can the genes communicate with each other after birth? An international cross‐sectional study Hashim, Hashim Talib Hashim, Ali Talib Nazir, Abubakar Afzaal, Usama Nazir, Awais Al‐Obaidi, Ahmed Dheyaa Health Sci Rep Original Research BACKGROUND: Various factors contribute to the pathogenesis of a disease. These include genetic factors, family history, and some idiopathic causes. Genetic makeup has an important role in the progression of disease. This is due to mutations in genetic material, that is, deoxyribonucleic acid (DNA). METHODOLOGY: This is a cross‐sectional study that involved 5000 participants distributed across 250 countries. All the participants were randomly selected and asked to fill out the online survey. All the participants were fully informed about the study's purpose before providing their consent. RESULTS: The participants were distributed among 250 countries. Their age mean (standard deviation) is 46.7 (12.4). We discovered a significant difference between those who have genetic or congenital diseases and those who have a family history of the disease. Also, there is a statistically significant difference between the recurrence of the disease and the duration of the visits of close relatives who have the same disease. CONCLUSION: The study suggests that there might be some ways, through gene waves or the environment, in which a gene changes the expression of other genes of similar sequence in different individuals when the required period of contact is provided. In the future, this theory might explain the idiopathic nature of some diseases. John Wiley and Sons Inc. 2023-01-30 /pmc/articles/PMC9885756/ /pubmed/36733667 http://dx.doi.org/10.1002/hsr2.1084 Text en © 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Hashim, Hashim Talib
Hashim, Ali Talib
Nazir, Abubakar
Afzaal, Usama
Nazir, Awais
Al‐Obaidi, Ahmed Dheyaa
Can the genes communicate with each other after birth? An international cross‐sectional study
title Can the genes communicate with each other after birth? An international cross‐sectional study
title_full Can the genes communicate with each other after birth? An international cross‐sectional study
title_fullStr Can the genes communicate with each other after birth? An international cross‐sectional study
title_full_unstemmed Can the genes communicate with each other after birth? An international cross‐sectional study
title_short Can the genes communicate with each other after birth? An international cross‐sectional study
title_sort can the genes communicate with each other after birth? an international cross‐sectional study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885756/
https://www.ncbi.nlm.nih.gov/pubmed/36733667
http://dx.doi.org/10.1002/hsr2.1084
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