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Safety and efficacy of minimally invasive percutaneous nephrolithotomy for infantile nephrolithiasis. Single centre experience from Pakistan

OBJECTIVE: To assess the efficacy and safety of mini-percutaneous nephrolithotomy (PCNL) for small renal stones 1–2 cm in size in infants less than one year. MATERIAL AND METHODS: This descriptive case series was conducted in the department of pediatric urology Institute of Kidney Diseases Peshawar,...

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Autores principales: Ahmad, Tariq, Minallah, Nasrum, Khaliq, Nida, Rashid, Hania, Syed, Misbah, Almuradi, Moath Ahmad Abdullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885957/
https://www.ncbi.nlm.nih.gov/pubmed/36726997
http://dx.doi.org/10.3389/fped.2022.1035964
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author Ahmad, Tariq
Minallah, Nasrum
Khaliq, Nida
Rashid, Hania
Syed, Misbah
Almuradi, Moath Ahmad Abdullah
author_facet Ahmad, Tariq
Minallah, Nasrum
Khaliq, Nida
Rashid, Hania
Syed, Misbah
Almuradi, Moath Ahmad Abdullah
author_sort Ahmad, Tariq
collection PubMed
description OBJECTIVE: To assess the efficacy and safety of mini-percutaneous nephrolithotomy (PCNL) for small renal stones 1–2 cm in size in infants less than one year. MATERIAL AND METHODS: This descriptive case series was conducted in the department of pediatric urology Institute of Kidney Diseases Peshawar, Pakistan, from March 2019 to March 2022. All the patients underwent mini-PCNL in prone position under GA with 14 Fr access sheath and 10 Fr nephroscope. Stone clearance was assessed by non-contrast CT KUB at 30th postoperative day. Patients with no residual fragments on the non-contrast CT KUB were defined as stone-free. Patients with residual fragments of any size were defined as procedure failure. Safety was determined in terms of intra and postoperative complications. RESULTS: A total of 51 infants were included in the study. The mean age of patients was 9.6 + 1.8 (5–12 month). The mean stone size was 15.8 + 2.7 (10–21) mm in length and 12.3 + 2.2 (8–17) mm in width. PCNL mean operative time was 51.6 ± 7.1 (40–70) minutes. Complete stone clearance at one month was observed in 46 (90.2%) patients. Residual fragments were seen in 5(9.8%) patients with a mean size of 1.6 + 0.4 (0.9–2.0) mm. None of the patients required any additional procedure for clearance of stones. In 7 (13.7%) patients, some post-operative complications were observe, all were grade I complications, including fever in 5(9.8%) and transient hematuria in 2(3.9%) patients. CONCLUSION: Mini-PCNL is a safe and effective treatment for renal stones in infants measuring 1–2 cm with high SFR and an acceptable complication rate.
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spelling pubmed-98859572023-01-31 Safety and efficacy of minimally invasive percutaneous nephrolithotomy for infantile nephrolithiasis. Single centre experience from Pakistan Ahmad, Tariq Minallah, Nasrum Khaliq, Nida Rashid, Hania Syed, Misbah Almuradi, Moath Ahmad Abdullah Front Pediatr Pediatrics OBJECTIVE: To assess the efficacy and safety of mini-percutaneous nephrolithotomy (PCNL) for small renal stones 1–2 cm in size in infants less than one year. MATERIAL AND METHODS: This descriptive case series was conducted in the department of pediatric urology Institute of Kidney Diseases Peshawar, Pakistan, from March 2019 to March 2022. All the patients underwent mini-PCNL in prone position under GA with 14 Fr access sheath and 10 Fr nephroscope. Stone clearance was assessed by non-contrast CT KUB at 30th postoperative day. Patients with no residual fragments on the non-contrast CT KUB were defined as stone-free. Patients with residual fragments of any size were defined as procedure failure. Safety was determined in terms of intra and postoperative complications. RESULTS: A total of 51 infants were included in the study. The mean age of patients was 9.6 + 1.8 (5–12 month). The mean stone size was 15.8 + 2.7 (10–21) mm in length and 12.3 + 2.2 (8–17) mm in width. PCNL mean operative time was 51.6 ± 7.1 (40–70) minutes. Complete stone clearance at one month was observed in 46 (90.2%) patients. Residual fragments were seen in 5(9.8%) patients with a mean size of 1.6 + 0.4 (0.9–2.0) mm. None of the patients required any additional procedure for clearance of stones. In 7 (13.7%) patients, some post-operative complications were observe, all were grade I complications, including fever in 5(9.8%) and transient hematuria in 2(3.9%) patients. CONCLUSION: Mini-PCNL is a safe and effective treatment for renal stones in infants measuring 1–2 cm with high SFR and an acceptable complication rate. Frontiers Media S.A. 2023-01-16 /pmc/articles/PMC9885957/ /pubmed/36726997 http://dx.doi.org/10.3389/fped.2022.1035964 Text en © 2023 Ahmad, Minallah, Khaliq, Rashid, Syed and Almuradi. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Ahmad, Tariq
Minallah, Nasrum
Khaliq, Nida
Rashid, Hania
Syed, Misbah
Almuradi, Moath Ahmad Abdullah
Safety and efficacy of minimally invasive percutaneous nephrolithotomy for infantile nephrolithiasis. Single centre experience from Pakistan
title Safety and efficacy of minimally invasive percutaneous nephrolithotomy for infantile nephrolithiasis. Single centre experience from Pakistan
title_full Safety and efficacy of minimally invasive percutaneous nephrolithotomy for infantile nephrolithiasis. Single centre experience from Pakistan
title_fullStr Safety and efficacy of minimally invasive percutaneous nephrolithotomy for infantile nephrolithiasis. Single centre experience from Pakistan
title_full_unstemmed Safety and efficacy of minimally invasive percutaneous nephrolithotomy for infantile nephrolithiasis. Single centre experience from Pakistan
title_short Safety and efficacy of minimally invasive percutaneous nephrolithotomy for infantile nephrolithiasis. Single centre experience from Pakistan
title_sort safety and efficacy of minimally invasive percutaneous nephrolithotomy for infantile nephrolithiasis. single centre experience from pakistan
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885957/
https://www.ncbi.nlm.nih.gov/pubmed/36726997
http://dx.doi.org/10.3389/fped.2022.1035964
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