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Serological and vaccine evaluation for hepatitis B among Community Health Workers
OBJECTIVE: to identify the vaccination and serological status against hepatitis B among community health workers; to vaccinate against hepatitis B virus and to evaluate the immune response of susceptible workers. METHOD: phase I, cross-sectional and descriptive study, among community health workers...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886073/ https://www.ncbi.nlm.nih.gov/pubmed/36722634 http://dx.doi.org/10.1590/1518-8345.6107.3765 |
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author | Amaral, Tauana de Souza Alves, Clery Mariano da Silva Rezende, Fabiana Ribeiro Caetano, Karlla Antonieta Amorim Tipple, Anaclara Ferreira Veiga |
author_facet | Amaral, Tauana de Souza Alves, Clery Mariano da Silva Rezende, Fabiana Ribeiro Caetano, Karlla Antonieta Amorim Tipple, Anaclara Ferreira Veiga |
author_sort | Amaral, Tauana de Souza |
collection | PubMed |
description | OBJECTIVE: to identify the vaccination and serological status against hepatitis B among community health workers; to vaccinate against hepatitis B virus and to evaluate the immune response of susceptible workers. METHOD: phase I, cross-sectional and descriptive study, among community health workers in a capital city of the Midwest region, through a self-administered questionnaire, checking of vaccination cards, and blood collection for testing of serological markers for hepatitis B. Phase II, cohort study carried out in vaccinated non-immune workers identified in phase I. They received one dose of vaccine (challenge dose) and serological testing. RESULTS: a total of 109 workers participated in the study. Most had vaccination record (97; 89.0%) and vaccination completeness (75; 77.3%), while the isolated anti-HBs (Antibodies against hepatitis B virus) marker was detected in 78 (71.6%) workers. The prevalence of hepatitis B virus exposure was 8.2%. Of the ten non-immune vaccinated workers, after challenge dose, one remained susceptible. CONCLUSION: although most workers are vaccinated and show immunological response to hepatitis B, susceptibility after challenge dose was identified. Therefore, it is necessary to have a surveillance program of the vaccination situation and serological status for this virus, to promote these workers’ safety. |
format | Online Article Text |
id | pubmed-9886073 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-98860732023-02-08 Serological and vaccine evaluation for hepatitis B among Community Health Workers Amaral, Tauana de Souza Alves, Clery Mariano da Silva Rezende, Fabiana Ribeiro Caetano, Karlla Antonieta Amorim Tipple, Anaclara Ferreira Veiga Rev Lat Am Enfermagem Original Article OBJECTIVE: to identify the vaccination and serological status against hepatitis B among community health workers; to vaccinate against hepatitis B virus and to evaluate the immune response of susceptible workers. METHOD: phase I, cross-sectional and descriptive study, among community health workers in a capital city of the Midwest region, through a self-administered questionnaire, checking of vaccination cards, and blood collection for testing of serological markers for hepatitis B. Phase II, cohort study carried out in vaccinated non-immune workers identified in phase I. They received one dose of vaccine (challenge dose) and serological testing. RESULTS: a total of 109 workers participated in the study. Most had vaccination record (97; 89.0%) and vaccination completeness (75; 77.3%), while the isolated anti-HBs (Antibodies against hepatitis B virus) marker was detected in 78 (71.6%) workers. The prevalence of hepatitis B virus exposure was 8.2%. Of the ten non-immune vaccinated workers, after challenge dose, one remained susceptible. CONCLUSION: although most workers are vaccinated and show immunological response to hepatitis B, susceptibility after challenge dose was identified. Therefore, it is necessary to have a surveillance program of the vaccination situation and serological status for this virus, to promote these workers’ safety. Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo 2023-01-30 /pmc/articles/PMC9886073/ /pubmed/36722634 http://dx.doi.org/10.1590/1518-8345.6107.3765 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License |
spellingShingle | Original Article Amaral, Tauana de Souza Alves, Clery Mariano da Silva Rezende, Fabiana Ribeiro Caetano, Karlla Antonieta Amorim Tipple, Anaclara Ferreira Veiga Serological and vaccine evaluation for hepatitis B among Community Health Workers |
title | Serological and vaccine evaluation for hepatitis B among Community Health Workers |
title_full | Serological and vaccine evaluation for hepatitis B among Community Health Workers |
title_fullStr | Serological and vaccine evaluation for hepatitis B among Community Health Workers |
title_full_unstemmed | Serological and vaccine evaluation for hepatitis B among Community Health Workers |
title_short | Serological and vaccine evaluation for hepatitis B among Community Health Workers |
title_sort | serological and vaccine evaluation for hepatitis b among community health workers |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886073/ https://www.ncbi.nlm.nih.gov/pubmed/36722634 http://dx.doi.org/10.1590/1518-8345.6107.3765 |
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