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Serological and vaccine evaluation for hepatitis B among Community Health Workers

OBJECTIVE: to identify the vaccination and serological status against hepatitis B among community health workers; to vaccinate against hepatitis B virus and to evaluate the immune response of susceptible workers. METHOD: phase I, cross-sectional and descriptive study, among community health workers...

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Autores principales: Amaral, Tauana de Souza, Alves, Clery Mariano da Silva, Rezende, Fabiana Ribeiro, Caetano, Karlla Antonieta Amorim, Tipple, Anaclara Ferreira Veiga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886073/
https://www.ncbi.nlm.nih.gov/pubmed/36722634
http://dx.doi.org/10.1590/1518-8345.6107.3765
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author Amaral, Tauana de Souza
Alves, Clery Mariano da Silva
Rezende, Fabiana Ribeiro
Caetano, Karlla Antonieta Amorim
Tipple, Anaclara Ferreira Veiga
author_facet Amaral, Tauana de Souza
Alves, Clery Mariano da Silva
Rezende, Fabiana Ribeiro
Caetano, Karlla Antonieta Amorim
Tipple, Anaclara Ferreira Veiga
author_sort Amaral, Tauana de Souza
collection PubMed
description OBJECTIVE: to identify the vaccination and serological status against hepatitis B among community health workers; to vaccinate against hepatitis B virus and to evaluate the immune response of susceptible workers. METHOD: phase I, cross-sectional and descriptive study, among community health workers in a capital city of the Midwest region, through a self-administered questionnaire, checking of vaccination cards, and blood collection for testing of serological markers for hepatitis B. Phase II, cohort study carried out in vaccinated non-immune workers identified in phase I. They received one dose of vaccine (challenge dose) and serological testing. RESULTS: a total of 109 workers participated in the study. Most had vaccination record (97; 89.0%) and vaccination completeness (75; 77.3%), while the isolated anti-HBs (Antibodies against hepatitis B virus) marker was detected in 78 (71.6%) workers. The prevalence of hepatitis B virus exposure was 8.2%. Of the ten non-immune vaccinated workers, after challenge dose, one remained susceptible. CONCLUSION: although most workers are vaccinated and show immunological response to hepatitis B, susceptibility after challenge dose was identified. Therefore, it is necessary to have a surveillance program of the vaccination situation and serological status for this virus, to promote these workers’ safety.
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spelling pubmed-98860732023-02-08 Serological and vaccine evaluation for hepatitis B among Community Health Workers Amaral, Tauana de Souza Alves, Clery Mariano da Silva Rezende, Fabiana Ribeiro Caetano, Karlla Antonieta Amorim Tipple, Anaclara Ferreira Veiga Rev Lat Am Enfermagem Original Article OBJECTIVE: to identify the vaccination and serological status against hepatitis B among community health workers; to vaccinate against hepatitis B virus and to evaluate the immune response of susceptible workers. METHOD: phase I, cross-sectional and descriptive study, among community health workers in a capital city of the Midwest region, through a self-administered questionnaire, checking of vaccination cards, and blood collection for testing of serological markers for hepatitis B. Phase II, cohort study carried out in vaccinated non-immune workers identified in phase I. They received one dose of vaccine (challenge dose) and serological testing. RESULTS: a total of 109 workers participated in the study. Most had vaccination record (97; 89.0%) and vaccination completeness (75; 77.3%), while the isolated anti-HBs (Antibodies against hepatitis B virus) marker was detected in 78 (71.6%) workers. The prevalence of hepatitis B virus exposure was 8.2%. Of the ten non-immune vaccinated workers, after challenge dose, one remained susceptible. CONCLUSION: although most workers are vaccinated and show immunological response to hepatitis B, susceptibility after challenge dose was identified. Therefore, it is necessary to have a surveillance program of the vaccination situation and serological status for this virus, to promote these workers’ safety. Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo 2023-01-30 /pmc/articles/PMC9886073/ /pubmed/36722634 http://dx.doi.org/10.1590/1518-8345.6107.3765 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
Amaral, Tauana de Souza
Alves, Clery Mariano da Silva
Rezende, Fabiana Ribeiro
Caetano, Karlla Antonieta Amorim
Tipple, Anaclara Ferreira Veiga
Serological and vaccine evaluation for hepatitis B among Community Health Workers
title Serological and vaccine evaluation for hepatitis B among Community Health Workers
title_full Serological and vaccine evaluation for hepatitis B among Community Health Workers
title_fullStr Serological and vaccine evaluation for hepatitis B among Community Health Workers
title_full_unstemmed Serological and vaccine evaluation for hepatitis B among Community Health Workers
title_short Serological and vaccine evaluation for hepatitis B among Community Health Workers
title_sort serological and vaccine evaluation for hepatitis b among community health workers
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886073/
https://www.ncbi.nlm.nih.gov/pubmed/36722634
http://dx.doi.org/10.1590/1518-8345.6107.3765
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