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Appendicitis Inflammatory Response Score in Acute Appendicitis: A Study at a Tertiary Care Center in North India

INTRODUCTION: Appendicitis is a common cause of acute abdominal pain. The diagnosis is eminently clinical and the cause is surgically correctable. However, a decision of surgery based on the clinical presentation only has a 15%–30% chance of the removal of a normal appendix. Thus, the diagnosis invo...

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Autores principales: Gupta, Varun, Gupta, Palak, Gill, Chiranjiv Singh, Gupta, Manvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886148/
https://www.ncbi.nlm.nih.gov/pubmed/36726654
http://dx.doi.org/10.4103/ijabmr.ijabmr_287_22
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author Gupta, Varun
Gupta, Palak
Gill, Chiranjiv Singh
Gupta, Manvi
author_facet Gupta, Varun
Gupta, Palak
Gill, Chiranjiv Singh
Gupta, Manvi
author_sort Gupta, Varun
collection PubMed
description INTRODUCTION: Appendicitis is a common cause of acute abdominal pain. The diagnosis is eminently clinical and the cause is surgically correctable. However, a decision of surgery based on the clinical presentation only has a 15%–30% chance of the removal of a normal appendix. Thus, the diagnosis involves a corroboration of clinical, laboratory, and radiological findings. Appendicitis scoring systems can be considered to expedite the diagnostic and decision-making process. AIM: The present study was conducted to study the efficacy of Appendicitis Inflammatory Response (AIR) score in the diagnosis of acute appendicitis and its correlation with the histopathological findings. MATERIALS AND METHODS: A cross-sectional study was conducted at a tertiary care center in North India comprising patients who presented to the surgery department with a provisional diagnosis of acute appendicitis and required appendectomy. RESULTS: Appendicitis was histopathologically proven in 54 patients. Patients with an AIR score ≥5 were 2.18 times more likely to have appendicitis. The probability of having appendicitis with AIR score ≥5 was 92.16% (positive predictive value). The diagnostic accuracy of AIR score was 82.81%. CONCLUSION: AIR score has a high sensitivity and positive predictive value in the diagnosis of acute appendicitis. It is a quick and convenient system for clinical evaluation of patients in primary care or peripheral hospitals where advanced facilities such as USG scan or CT scan are not available all the time. The application of this scoring system definitely improves diagnostic accuracy and reduces negative appendectomy rate.
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spelling pubmed-98861482023-01-31 Appendicitis Inflammatory Response Score in Acute Appendicitis: A Study at a Tertiary Care Center in North India Gupta, Varun Gupta, Palak Gill, Chiranjiv Singh Gupta, Manvi Int J Appl Basic Med Res Original Article INTRODUCTION: Appendicitis is a common cause of acute abdominal pain. The diagnosis is eminently clinical and the cause is surgically correctable. However, a decision of surgery based on the clinical presentation only has a 15%–30% chance of the removal of a normal appendix. Thus, the diagnosis involves a corroboration of clinical, laboratory, and radiological findings. Appendicitis scoring systems can be considered to expedite the diagnostic and decision-making process. AIM: The present study was conducted to study the efficacy of Appendicitis Inflammatory Response (AIR) score in the diagnosis of acute appendicitis and its correlation with the histopathological findings. MATERIALS AND METHODS: A cross-sectional study was conducted at a tertiary care center in North India comprising patients who presented to the surgery department with a provisional diagnosis of acute appendicitis and required appendectomy. RESULTS: Appendicitis was histopathologically proven in 54 patients. Patients with an AIR score ≥5 were 2.18 times more likely to have appendicitis. The probability of having appendicitis with AIR score ≥5 was 92.16% (positive predictive value). The diagnostic accuracy of AIR score was 82.81%. CONCLUSION: AIR score has a high sensitivity and positive predictive value in the diagnosis of acute appendicitis. It is a quick and convenient system for clinical evaluation of patients in primary care or peripheral hospitals where advanced facilities such as USG scan or CT scan are not available all the time. The application of this scoring system definitely improves diagnostic accuracy and reduces negative appendectomy rate. Wolters Kluwer - Medknow 2022 2022-12-19 /pmc/articles/PMC9886148/ /pubmed/36726654 http://dx.doi.org/10.4103/ijabmr.ijabmr_287_22 Text en Copyright: © 2022 International Journal of Applied and Basic Medical Research https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Gupta, Varun
Gupta, Palak
Gill, Chiranjiv Singh
Gupta, Manvi
Appendicitis Inflammatory Response Score in Acute Appendicitis: A Study at a Tertiary Care Center in North India
title Appendicitis Inflammatory Response Score in Acute Appendicitis: A Study at a Tertiary Care Center in North India
title_full Appendicitis Inflammatory Response Score in Acute Appendicitis: A Study at a Tertiary Care Center in North India
title_fullStr Appendicitis Inflammatory Response Score in Acute Appendicitis: A Study at a Tertiary Care Center in North India
title_full_unstemmed Appendicitis Inflammatory Response Score in Acute Appendicitis: A Study at a Tertiary Care Center in North India
title_short Appendicitis Inflammatory Response Score in Acute Appendicitis: A Study at a Tertiary Care Center in North India
title_sort appendicitis inflammatory response score in acute appendicitis: a study at a tertiary care center in north india
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886148/
https://www.ncbi.nlm.nih.gov/pubmed/36726654
http://dx.doi.org/10.4103/ijabmr.ijabmr_287_22
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