A Case of Digital Cutaneous Melanocytic Tumor With CRTC1::TRIM11 Fusion

A cutaneous melanocytic tumor with CRTC1::TRIM11 fusion (CMTCT) was recently described as a novel superficial tumor with melanocytic differentiation and harboring a unique in-frame translocation, CRTC1::TRIM11. This emerging entity can occur at any age and is known to be a low-grade malignant neopla...

Descripción completa

Detalles Bibliográficos
Autores principales: Bui, Chau M, Chaum, Manita, Balzer, Bonnie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886156/
https://www.ncbi.nlm.nih.gov/pubmed/36726909
http://dx.doi.org/10.7759/cureus.33179
_version_ 1784880077608058880
author Bui, Chau M
Chaum, Manita
Balzer, Bonnie
author_facet Bui, Chau M
Chaum, Manita
Balzer, Bonnie
author_sort Bui, Chau M
collection PubMed
description A cutaneous melanocytic tumor with CRTC1::TRIM11 fusion (CMTCT) was recently described as a novel superficial tumor with melanocytic differentiation and harboring a unique in-frame translocation, CRTC1::TRIM11. This emerging entity can occur at any age and is known to be a low-grade malignant neoplasm with limited follow-up data. There are no available guidelines for the management and treatment of this tumor. This neoplasm has been found in the extremities, head and neck, and trunk. Here, we present the first case occurring on acral digital skin. This case contributes to the growing knowledge surrounding this newly described entity.
format Online
Article
Text
id pubmed-9886156
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-98861562023-01-31 A Case of Digital Cutaneous Melanocytic Tumor With CRTC1::TRIM11 Fusion Bui, Chau M Chaum, Manita Balzer, Bonnie Cureus Genetics A cutaneous melanocytic tumor with CRTC1::TRIM11 fusion (CMTCT) was recently described as a novel superficial tumor with melanocytic differentiation and harboring a unique in-frame translocation, CRTC1::TRIM11. This emerging entity can occur at any age and is known to be a low-grade malignant neoplasm with limited follow-up data. There are no available guidelines for the management and treatment of this tumor. This neoplasm has been found in the extremities, head and neck, and trunk. Here, we present the first case occurring on acral digital skin. This case contributes to the growing knowledge surrounding this newly described entity. Cureus 2022-12-31 /pmc/articles/PMC9886156/ /pubmed/36726909 http://dx.doi.org/10.7759/cureus.33179 Text en Copyright © 2022, Bui et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Genetics
Bui, Chau M
Chaum, Manita
Balzer, Bonnie
A Case of Digital Cutaneous Melanocytic Tumor With CRTC1::TRIM11 Fusion
title A Case of Digital Cutaneous Melanocytic Tumor With CRTC1::TRIM11 Fusion
title_full A Case of Digital Cutaneous Melanocytic Tumor With CRTC1::TRIM11 Fusion
title_fullStr A Case of Digital Cutaneous Melanocytic Tumor With CRTC1::TRIM11 Fusion
title_full_unstemmed A Case of Digital Cutaneous Melanocytic Tumor With CRTC1::TRIM11 Fusion
title_short A Case of Digital Cutaneous Melanocytic Tumor With CRTC1::TRIM11 Fusion
title_sort case of digital cutaneous melanocytic tumor with crtc1::trim11 fusion
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886156/
https://www.ncbi.nlm.nih.gov/pubmed/36726909
http://dx.doi.org/10.7759/cureus.33179
work_keys_str_mv AT buichaum acaseofdigitalcutaneousmelanocytictumorwithcrtc1trim11fusion
AT chaummanita acaseofdigitalcutaneousmelanocytictumorwithcrtc1trim11fusion
AT balzerbonnie acaseofdigitalcutaneousmelanocytictumorwithcrtc1trim11fusion
AT buichaum caseofdigitalcutaneousmelanocytictumorwithcrtc1trim11fusion
AT chaummanita caseofdigitalcutaneousmelanocytictumorwithcrtc1trim11fusion
AT balzerbonnie caseofdigitalcutaneousmelanocytictumorwithcrtc1trim11fusion

Ejemplares similares