Cargando…
ROS is a master regulator of in vitro matriptase activation
Matriptase is a type II transmembrane serine protease that is widely expressed in normal epithelial cells and epithelial cancers. Studies have shown that regulation of matriptase expression and activation becomes deranged in several cancers and is associated with poor disease-free survival. Although...
Autores principales: | Gaymon, Darius O., Barndt, Robert, Stires, Hillary, Riggins, Rebecca B., Johnson, Michael. D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886240/ https://www.ncbi.nlm.nih.gov/pubmed/36716335 http://dx.doi.org/10.1371/journal.pone.0267492 |
Ejemplares similares
-
Matriptase shedding is closely coupled with matriptase zymogen activation and requires de novo proteolytic cleavage likely involving its own activity
por: Tseng, Chun-Che, et al.
Publicado: (2017) -
Matriptase regulates proliferation and early, but not terminal, differentiation of human keratinocytes
por: Chen, Ya-Wen, et al.
Publicado: (2013) -
Aberrant regulation favours matriptase proteolysis in neoplastic B-cells that co-express HAI-2
por: Chiu, Yi-Lin, et al.
Publicado: (2019) -
Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner
por: Su, Hui Chen, et al.
Publicado: (2016) -
The intracellular seven amino acid motif EEGEVFL is required for matriptase vesicle sorting and translocation to the basolateral plasma membrane
por: Tseng, Chun-Che, et al.
Publicado: (2020)