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Association of sarcopenia with important health conditions among community-dwelling Asian women

This study aimed to examine sarcopenia prevalence using the Asian Working Group for Sarcopenia 2019 (AWGS) and the Foundation for the National Institutes of Health (FNIH) definitions, and their associations with important health conditions affecting midlife Singaporean women. Muscle mass and functio...

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Autores principales: Wong, Beverly Wen-Xin, Thu, Win Pa Pa, Chan, Yiong Huak, Logan, Susan Jane Sinclair, Cauley, Jane A., Yong, Eu-Leong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886252/
https://www.ncbi.nlm.nih.gov/pubmed/36716336
http://dx.doi.org/10.1371/journal.pone.0281144
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author Wong, Beverly Wen-Xin
Thu, Win Pa Pa
Chan, Yiong Huak
Logan, Susan Jane Sinclair
Cauley, Jane A.
Yong, Eu-Leong
author_facet Wong, Beverly Wen-Xin
Thu, Win Pa Pa
Chan, Yiong Huak
Logan, Susan Jane Sinclair
Cauley, Jane A.
Yong, Eu-Leong
author_sort Wong, Beverly Wen-Xin
collection PubMed
description This study aimed to examine sarcopenia prevalence using the Asian Working Group for Sarcopenia 2019 (AWGS) and the Foundation for the National Institutes of Health (FNIH) definitions, and their associations with important health conditions affecting midlife Singaporean women. Muscle mass and function were objectively assessed in 1201 healthy community-dwelling subjects aged 45–69 years under the Integrated Women’s Health Program (IWHP). Dual-energy X-ray absorptiometry (DXA), handgrip strength and the Short Physical Performance Battery (SPPB) were measured, and the relationship between sarcopenia with hypertension, type 2 diabetes (T2DM), osteoporosis, depression/anxiety, and urinary incontinence were examined using binary logistic regression models. Sarcopenia prevalence was 18.0% and 7.7% by the AWGS and FNIH criteria respectively. Osteoporosis (aOR: 1.74, 95% CI: 1.02, 2.94) and T2DM (aOR: 1.98, 95% CI: 1.14, 3.42) was positively associated with AWGS- and FNIH-defined sarcopenia respectively, while hypertension was not, after adjustment for age, ethnicity, education levels and menopausal status. A negative percent agreement of 95.6% suggests good agreement between the criteria in the absence of sarcopenia. Even though they represent a single concept, sarcopenia by either criterion differed in their relationships with diabetes and osteoporosis, suggesting the need for further rationalization of diagnostic criteria.
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spelling pubmed-98862522023-01-31 Association of sarcopenia with important health conditions among community-dwelling Asian women Wong, Beverly Wen-Xin Thu, Win Pa Pa Chan, Yiong Huak Logan, Susan Jane Sinclair Cauley, Jane A. Yong, Eu-Leong PLoS One Research Article This study aimed to examine sarcopenia prevalence using the Asian Working Group for Sarcopenia 2019 (AWGS) and the Foundation for the National Institutes of Health (FNIH) definitions, and their associations with important health conditions affecting midlife Singaporean women. Muscle mass and function were objectively assessed in 1201 healthy community-dwelling subjects aged 45–69 years under the Integrated Women’s Health Program (IWHP). Dual-energy X-ray absorptiometry (DXA), handgrip strength and the Short Physical Performance Battery (SPPB) were measured, and the relationship between sarcopenia with hypertension, type 2 diabetes (T2DM), osteoporosis, depression/anxiety, and urinary incontinence were examined using binary logistic regression models. Sarcopenia prevalence was 18.0% and 7.7% by the AWGS and FNIH criteria respectively. Osteoporosis (aOR: 1.74, 95% CI: 1.02, 2.94) and T2DM (aOR: 1.98, 95% CI: 1.14, 3.42) was positively associated with AWGS- and FNIH-defined sarcopenia respectively, while hypertension was not, after adjustment for age, ethnicity, education levels and menopausal status. A negative percent agreement of 95.6% suggests good agreement between the criteria in the absence of sarcopenia. Even though they represent a single concept, sarcopenia by either criterion differed in their relationships with diabetes and osteoporosis, suggesting the need for further rationalization of diagnostic criteria. Public Library of Science 2023-01-30 /pmc/articles/PMC9886252/ /pubmed/36716336 http://dx.doi.org/10.1371/journal.pone.0281144 Text en © 2023 Wong et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Wong, Beverly Wen-Xin
Thu, Win Pa Pa
Chan, Yiong Huak
Logan, Susan Jane Sinclair
Cauley, Jane A.
Yong, Eu-Leong
Association of sarcopenia with important health conditions among community-dwelling Asian women
title Association of sarcopenia with important health conditions among community-dwelling Asian women
title_full Association of sarcopenia with important health conditions among community-dwelling Asian women
title_fullStr Association of sarcopenia with important health conditions among community-dwelling Asian women
title_full_unstemmed Association of sarcopenia with important health conditions among community-dwelling Asian women
title_short Association of sarcopenia with important health conditions among community-dwelling Asian women
title_sort association of sarcopenia with important health conditions among community-dwelling asian women
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886252/
https://www.ncbi.nlm.nih.gov/pubmed/36716336
http://dx.doi.org/10.1371/journal.pone.0281144
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