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Association of sarcopenia with important health conditions among community-dwelling Asian women
This study aimed to examine sarcopenia prevalence using the Asian Working Group for Sarcopenia 2019 (AWGS) and the Foundation for the National Institutes of Health (FNIH) definitions, and their associations with important health conditions affecting midlife Singaporean women. Muscle mass and functio...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886252/ https://www.ncbi.nlm.nih.gov/pubmed/36716336 http://dx.doi.org/10.1371/journal.pone.0281144 |
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author | Wong, Beverly Wen-Xin Thu, Win Pa Pa Chan, Yiong Huak Logan, Susan Jane Sinclair Cauley, Jane A. Yong, Eu-Leong |
author_facet | Wong, Beverly Wen-Xin Thu, Win Pa Pa Chan, Yiong Huak Logan, Susan Jane Sinclair Cauley, Jane A. Yong, Eu-Leong |
author_sort | Wong, Beverly Wen-Xin |
collection | PubMed |
description | This study aimed to examine sarcopenia prevalence using the Asian Working Group for Sarcopenia 2019 (AWGS) and the Foundation for the National Institutes of Health (FNIH) definitions, and their associations with important health conditions affecting midlife Singaporean women. Muscle mass and function were objectively assessed in 1201 healthy community-dwelling subjects aged 45–69 years under the Integrated Women’s Health Program (IWHP). Dual-energy X-ray absorptiometry (DXA), handgrip strength and the Short Physical Performance Battery (SPPB) were measured, and the relationship between sarcopenia with hypertension, type 2 diabetes (T2DM), osteoporosis, depression/anxiety, and urinary incontinence were examined using binary logistic regression models. Sarcopenia prevalence was 18.0% and 7.7% by the AWGS and FNIH criteria respectively. Osteoporosis (aOR: 1.74, 95% CI: 1.02, 2.94) and T2DM (aOR: 1.98, 95% CI: 1.14, 3.42) was positively associated with AWGS- and FNIH-defined sarcopenia respectively, while hypertension was not, after adjustment for age, ethnicity, education levels and menopausal status. A negative percent agreement of 95.6% suggests good agreement between the criteria in the absence of sarcopenia. Even though they represent a single concept, sarcopenia by either criterion differed in their relationships with diabetes and osteoporosis, suggesting the need for further rationalization of diagnostic criteria. |
format | Online Article Text |
id | pubmed-9886252 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-98862522023-01-31 Association of sarcopenia with important health conditions among community-dwelling Asian women Wong, Beverly Wen-Xin Thu, Win Pa Pa Chan, Yiong Huak Logan, Susan Jane Sinclair Cauley, Jane A. Yong, Eu-Leong PLoS One Research Article This study aimed to examine sarcopenia prevalence using the Asian Working Group for Sarcopenia 2019 (AWGS) and the Foundation for the National Institutes of Health (FNIH) definitions, and their associations with important health conditions affecting midlife Singaporean women. Muscle mass and function were objectively assessed in 1201 healthy community-dwelling subjects aged 45–69 years under the Integrated Women’s Health Program (IWHP). Dual-energy X-ray absorptiometry (DXA), handgrip strength and the Short Physical Performance Battery (SPPB) were measured, and the relationship between sarcopenia with hypertension, type 2 diabetes (T2DM), osteoporosis, depression/anxiety, and urinary incontinence were examined using binary logistic regression models. Sarcopenia prevalence was 18.0% and 7.7% by the AWGS and FNIH criteria respectively. Osteoporosis (aOR: 1.74, 95% CI: 1.02, 2.94) and T2DM (aOR: 1.98, 95% CI: 1.14, 3.42) was positively associated with AWGS- and FNIH-defined sarcopenia respectively, while hypertension was not, after adjustment for age, ethnicity, education levels and menopausal status. A negative percent agreement of 95.6% suggests good agreement between the criteria in the absence of sarcopenia. Even though they represent a single concept, sarcopenia by either criterion differed in their relationships with diabetes and osteoporosis, suggesting the need for further rationalization of diagnostic criteria. Public Library of Science 2023-01-30 /pmc/articles/PMC9886252/ /pubmed/36716336 http://dx.doi.org/10.1371/journal.pone.0281144 Text en © 2023 Wong et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Wong, Beverly Wen-Xin Thu, Win Pa Pa Chan, Yiong Huak Logan, Susan Jane Sinclair Cauley, Jane A. Yong, Eu-Leong Association of sarcopenia with important health conditions among community-dwelling Asian women |
title | Association of sarcopenia with important health conditions among community-dwelling Asian women |
title_full | Association of sarcopenia with important health conditions among community-dwelling Asian women |
title_fullStr | Association of sarcopenia with important health conditions among community-dwelling Asian women |
title_full_unstemmed | Association of sarcopenia with important health conditions among community-dwelling Asian women |
title_short | Association of sarcopenia with important health conditions among community-dwelling Asian women |
title_sort | association of sarcopenia with important health conditions among community-dwelling asian women |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886252/ https://www.ncbi.nlm.nih.gov/pubmed/36716336 http://dx.doi.org/10.1371/journal.pone.0281144 |
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