A Rare Case of Metastatic Gastric Signet Ring Cell Adenocarcinoma in a 23-Year-Old Female Presenting as Malignant Pleural Effusion

Signet ring cell carcinoma (SRCC) is a poorly differentiated mucin-producing adenocarcinoma with greater than 50% signet ring cells. It commonly arises from the gastrointestinal (GI) tract and rarely from extraintestinal organs. This is a rare case of a young African American female who presented wi...

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Autores principales: Torere, Beatrice E, Aiwuyo, Henry O, Ilerhunmwuwa, Nosakhare, Raza, Hafiz M, Tan, Jiahuai, Belousova, Tatiana, Wasifuddin, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886370/
https://www.ncbi.nlm.nih.gov/pubmed/36726911
http://dx.doi.org/10.7759/cureus.33085
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author Torere, Beatrice E
Aiwuyo, Henry O
Ilerhunmwuwa, Nosakhare
Raza, Hafiz M
Tan, Jiahuai
Belousova, Tatiana
Wasifuddin, Mustafa
author_facet Torere, Beatrice E
Aiwuyo, Henry O
Ilerhunmwuwa, Nosakhare
Raza, Hafiz M
Tan, Jiahuai
Belousova, Tatiana
Wasifuddin, Mustafa
author_sort Torere, Beatrice E
collection PubMed
description Signet ring cell carcinoma (SRCC) is a poorly differentiated mucin-producing adenocarcinoma with greater than 50% signet ring cells. It commonly arises from the gastrointestinal (GI) tract and rarely from extraintestinal organs. This is a rare case of a young African American female who presented with metastatic spread of signet ring cell gastric cancer (pleural and lymph nodal involvement) as the initial presentation of SRCC. Knowledge of the various clinical manifestations of SRCC can help with its early diagnosis, and there is a high need for detailed physical examination, early referral, and prompt treatment in patients with SRCC.
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spelling pubmed-98863702023-01-31 A Rare Case of Metastatic Gastric Signet Ring Cell Adenocarcinoma in a 23-Year-Old Female Presenting as Malignant Pleural Effusion Torere, Beatrice E Aiwuyo, Henry O Ilerhunmwuwa, Nosakhare Raza, Hafiz M Tan, Jiahuai Belousova, Tatiana Wasifuddin, Mustafa Cureus Internal Medicine Signet ring cell carcinoma (SRCC) is a poorly differentiated mucin-producing adenocarcinoma with greater than 50% signet ring cells. It commonly arises from the gastrointestinal (GI) tract and rarely from extraintestinal organs. This is a rare case of a young African American female who presented with metastatic spread of signet ring cell gastric cancer (pleural and lymph nodal involvement) as the initial presentation of SRCC. Knowledge of the various clinical manifestations of SRCC can help with its early diagnosis, and there is a high need for detailed physical examination, early referral, and prompt treatment in patients with SRCC. Cureus 2022-12-29 /pmc/articles/PMC9886370/ /pubmed/36726911 http://dx.doi.org/10.7759/cureus.33085 Text en Copyright © 2022, Torere et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Torere, Beatrice E
Aiwuyo, Henry O
Ilerhunmwuwa, Nosakhare
Raza, Hafiz M
Tan, Jiahuai
Belousova, Tatiana
Wasifuddin, Mustafa
A Rare Case of Metastatic Gastric Signet Ring Cell Adenocarcinoma in a 23-Year-Old Female Presenting as Malignant Pleural Effusion
title A Rare Case of Metastatic Gastric Signet Ring Cell Adenocarcinoma in a 23-Year-Old Female Presenting as Malignant Pleural Effusion
title_full A Rare Case of Metastatic Gastric Signet Ring Cell Adenocarcinoma in a 23-Year-Old Female Presenting as Malignant Pleural Effusion
title_fullStr A Rare Case of Metastatic Gastric Signet Ring Cell Adenocarcinoma in a 23-Year-Old Female Presenting as Malignant Pleural Effusion
title_full_unstemmed A Rare Case of Metastatic Gastric Signet Ring Cell Adenocarcinoma in a 23-Year-Old Female Presenting as Malignant Pleural Effusion
title_short A Rare Case of Metastatic Gastric Signet Ring Cell Adenocarcinoma in a 23-Year-Old Female Presenting as Malignant Pleural Effusion
title_sort rare case of metastatic gastric signet ring cell adenocarcinoma in a 23-year-old female presenting as malignant pleural effusion
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886370/
https://www.ncbi.nlm.nih.gov/pubmed/36726911
http://dx.doi.org/10.7759/cureus.33085
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