Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis

The AURORA US Metastasis Project was established with the goal to identify molecular features associated with metastasis. We assayed 55 females with metastatic breast cancer (51 primary cancers and 102 metastases) by RNA sequencing, tumor/germline DNA exome and low-pass whole-genome sequencing and g...

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Detalles Bibliográficos
Autores principales: Garcia-Recio, Susana, Hinoue, Toshinori, Wheeler, Gregory L., Kelly, Benjamin J., Garrido-Castro, Ana C., Pascual, Tomas, De Cubas, Aguirre A., Xia, Youli, Felsheim, Brooke M., McClure, Marni B., Rajkovic, Andrei, Karaesmen, Ezgi, Smith, Markia A., Fan, Cheng, Ericsson, Paula I. Gonzalez, Sanders, Melinda E., Creighton, Chad J., Bowen, Jay, Leraas, Kristen, Burns, Robyn T., Coppens, Sara, Wheless, Amy, Rezk, Salma, Garrett, Amy L., Parker, Joel S., Foy, Kelly K., Shen, Hui, Park, Ben H., Krop, Ian, Anders, Carey, Gastier-Foster, Julie, Rimawi, Mothaffar F., Nanda, Rita, Lin, Nancy U., Isaacs, Claudine, Marcom, P. Kelly, Storniolo, Anna Maria, Couch, Fergus J., Chandran, Uma, Davis, Michael, Silverstein, Jonathan, Ropelewski, Alexander, Liu, Minetta C., Hilsenbeck, Susan G., Norton, Larry, Richardson, Andrea L., Symmans, W. Fraser, Wolff, Antonio C., Davidson, Nancy E., Carey, Lisa A., Lee, Adrian V., Balko, Justin M., Hoadley, Katherine A., Laird, Peter W., Mardis, Elaine R., King, Tari A., Perou, Charles M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886551/
https://www.ncbi.nlm.nih.gov/pubmed/36585450
http://dx.doi.org/10.1038/s43018-022-00491-x

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