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Risk scores in cardiac resynchronization therapy–A review of the literature

Cardiac resynchronization therapy (CRT) for selected heart failure (HF) patients improves symptoms and reduces morbidity and mortality; however, the prognosis of HF is still poor. There is an emerging need for tools that might help in optimal patient selection and provide prognostic information for...

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Autores principales: Boros, András Mihály, Perge, Péter, Merkely, Béla, Széplaki, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886679/
https://www.ncbi.nlm.nih.gov/pubmed/36733831
http://dx.doi.org/10.3389/fcvm.2022.1048673
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author Boros, András Mihály
Perge, Péter
Merkely, Béla
Széplaki, Gábor
author_facet Boros, András Mihály
Perge, Péter
Merkely, Béla
Széplaki, Gábor
author_sort Boros, András Mihály
collection PubMed
description Cardiac resynchronization therapy (CRT) for selected heart failure (HF) patients improves symptoms and reduces morbidity and mortality; however, the prognosis of HF is still poor. There is an emerging need for tools that might help in optimal patient selection and provide prognostic information for patients and their families. Several risk scores have been created in recent years; although, no literature review is available that would list the possible scores for the clinicians. We identified forty-eight risk scores in CRT and provided the calculation methods and formulas in a ready-to-use format. The reviewed score systems can predict the prognosis of CRT patients; some of them have even provided an online calculation tool. Significant heterogeneity is present between the various risk scores in terms of the variables incorporated and some variables are not yet used in daily clinical practice. The lack of cross-validation of the risk scores limits their routine use and objective selection. As the number of prognostic markers of CRT is overwhelming, further studies might be required to analyze and cross-validate the data.
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spelling pubmed-98866792023-02-01 Risk scores in cardiac resynchronization therapy–A review of the literature Boros, András Mihály Perge, Péter Merkely, Béla Széplaki, Gábor Front Cardiovasc Med Cardiovascular Medicine Cardiac resynchronization therapy (CRT) for selected heart failure (HF) patients improves symptoms and reduces morbidity and mortality; however, the prognosis of HF is still poor. There is an emerging need for tools that might help in optimal patient selection and provide prognostic information for patients and their families. Several risk scores have been created in recent years; although, no literature review is available that would list the possible scores for the clinicians. We identified forty-eight risk scores in CRT and provided the calculation methods and formulas in a ready-to-use format. The reviewed score systems can predict the prognosis of CRT patients; some of them have even provided an online calculation tool. Significant heterogeneity is present between the various risk scores in terms of the variables incorporated and some variables are not yet used in daily clinical practice. The lack of cross-validation of the risk scores limits their routine use and objective selection. As the number of prognostic markers of CRT is overwhelming, further studies might be required to analyze and cross-validate the data. Frontiers Media S.A. 2023-01-17 /pmc/articles/PMC9886679/ /pubmed/36733831 http://dx.doi.org/10.3389/fcvm.2022.1048673 Text en Copyright © 2023 Boros, Perge, Merkely and Széplaki. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Boros, András Mihály
Perge, Péter
Merkely, Béla
Széplaki, Gábor
Risk scores in cardiac resynchronization therapy–A review of the literature
title Risk scores in cardiac resynchronization therapy–A review of the literature
title_full Risk scores in cardiac resynchronization therapy–A review of the literature
title_fullStr Risk scores in cardiac resynchronization therapy–A review of the literature
title_full_unstemmed Risk scores in cardiac resynchronization therapy–A review of the literature
title_short Risk scores in cardiac resynchronization therapy–A review of the literature
title_sort risk scores in cardiac resynchronization therapy–a review of the literature
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886679/
https://www.ncbi.nlm.nih.gov/pubmed/36733831
http://dx.doi.org/10.3389/fcvm.2022.1048673
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