High polygenic risk score for exceptional longevity is associated with a healthy metabolic profile

Healthy metabolic measures in humans are associated with longevity. Dysregulation leads to metabolic syndrome (MetS) and negative health outcomes. Recent exceptional longevity (EL) genome wide association studies have facilitated estimation of an individual’s polygenic risk score (PRS) for EL. We te...

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Detalles Bibliográficos
Autores principales: Revelas, Mary, Thalamuthu, Anbupalam, Zettergren, Anna, Oldmeadow, Christopher, Najar, Jenna, Seidu, Nazib M., Armstrong, Nicola J., Riveros, Carlos, Kwok, John B., Schofield, Peter R., Trollor, Julian N., Waern, Margda, Wright, Margaret J., Zetterberg, Henrik, Ames, David, Belnnow, Kaj, Brodaty, Henry, Scott, Rodney J., Skoog, Ingmar, Attia, John R., Sachdev, Perminder S., Mather, Karen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886704/
https://www.ncbi.nlm.nih.gov/pubmed/35972662
http://dx.doi.org/10.1007/s11357-022-00643-y

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