Cargando…

The Role of Caspase Family in Acute Brain Injury: The Potential Therapeutic Targets in the Future

The caspase family is commonly involved in the pathophysiology of acute brain injury (ABI) through complex apoptotic, pyroptotic, and inflammatory pathways. Current translational strategies for caspase modulation in ABI primarily focus on caspase inhibitors. Because there are no caspase-inhibiting d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Anke, Zhang, Zeyu, Liu, Yibo, Lenahan, Cameron, Xu, Houshi, Jiang, Junkun, Yuan, Ling, Wang, Liangbo, Xu, Yuanzhi, Chen, Sheng, Fang, Yuanjian, Zhang, Jianmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2022
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886824/ https://www.ncbi.nlm.nih.gov/pubmed/34766893 http://dx.doi.org/10.2174/1570159X19666211111121146

Ejemplares similares

CCL17 exerts neuroprotection through activation of CCR4/mTORC2 axis in microglia after subarachnoid haemorrhage in rats
por: Zhang, Anke, et al.
Publicado: (2022)

New Mechanisms and Targets of Subarachnoid Hemorrhage: A Focus on Mitochondria
por: Zhang, Zeyu, et al.
Publicado: (2022)

New Insights of Early Brain Injury after Subarachnoid Hemorrhage: A Focus on the Caspase Family
por: Wang, Xiaoyu, et al.
Publicado: (2023)

Effect of stress‐induced hyperglycemia after non‐traumatic non‐aneurysmal subarachnoid hemorrhage on clinical complications and functional outcomes
por: Zhang, Zeyu, et al.
Publicado: (2022)

Establishment of a nomogram with EMP3 for predicting clinical outcomes in patients with glioma: A bi‐center study
por: Zhang, Anke, et al.
Publicado: (2021)

TRP Family Genes Are Differently Expressed and Correlated with Immune Response in Glioma
por: Fang, Chaoyou, et al.
Publicado: (2022)

Inhibition of caspase-1-mediated inflammasome activation reduced blood coagulation in cerebrospinal fluid after subarachnoid haemorrhage
por: Fang, Yuanjian, et al.
Publicado: (2022)

Development of a nomogram for predicting clinical outcome in patients with angiogram‐negative subarachnoid hemorrhage
por: Zhang, Anke, et al.
Publicado: (2021)

Anoikis resistance in diffuse glioma: The potential therapeutic targets in the future
por: Zhu, Zhengyang, et al.
Publicado: (2022)

Connection between oxidative stress and subcellular organelle in subarachnoid hemorrhage: Novel mechanisms and therapeutic implications
por: Zhang, Jiahao, et al.
Publicado: (2023)

Natural Products for the Treatment of Post-stroke Depression
por: Fang, Chaoyou, et al.
Publicado: (2022)

Pleiotropic Role of Tenascin-C in Central Nervous System Diseases: From Basic to Clinical Applications
por: Hanmin, Chen, et al.
Publicado: (2020)

Natural Compounds for SIRT1-Mediated Oxidative Stress and Neuroinflammation in Stroke: A Potential Therapeutic Target in the Future
por: Fang, Chaoyou, et al.
Publicado: (2022)

SLC11A1 as a stratification indicator for immunotherapy or chemotherapy in patients with glioma
por: Xu, Houshi, et al.
Publicado: (2022)

Spotlight on clinical strategies of Chronic Internal Carotid Artery Occlusion: Endovascular interventions and external-intracarotid bypasses compared to conservative treatment
por: Wu, Junnan, et al.
Publicado: (2022)

Prognostic and predictive value of FCER1G in glioma outcomes and response to immunotherapy
por: Xu, Houshi, et al.
Publicado: (2021)

HIF-1α Mediates TRAIL-Induced Neuronal Apoptosis via Regulating DcR1 Expression Following Traumatic Brain Injury
por: Fang, Yuanjian, et al.
Publicado: (2020)

The Updated Role of the Blood Brain Barrier in Subarachnoid Hemorrhage: From Basic and Clinical Studies
por: Chen, Sheng, et al.
Publicado: (2020)

Selective autophagy as a therapeutic target for neurological diseases
por: Xu, Weilin, et al.
Publicado: (2020)

Validation and Comparison of Aneurysmal Subarachnoid Hemorrhage Grading Scales in Angiogram-Negative Subarachnoid Hemorrhage Patients
por: Fang, Yuanjian, et al.
Publicado: (2020)

Clinical Potential of Immunotherapies in Subarachnoid Hemorrhage Treatment: Mechanistic Dissection of Innate and Adaptive Immune Responses
por: Zhang, Anke, et al.
Publicado: (2023)

Ferroptosis in Acute Central Nervous System Injuries: The Future Direction?
por: Shen, Lesang, et al.
Publicado: (2020)

Prognosis Analysis and Validation of m(6)A Signature and Tumor Immune Microenvironment in Glioma
por: Lin, Shaojian, et al.
Publicado: (2020)

Programmed Cell Deaths and Potential Crosstalk With Blood–Brain Barrier Dysfunction After Hemorrhagic Stroke
por: Fang, Yuanjian, et al.
Publicado: (2020)

Comparison of aneurysmal subarachnoid hemorrhage grading scores in patients with aneurysm clipping and coiling
por: Fang, Yuanjian, et al.
Publicado: (2020)

Inhibition of Caspase 3 and Caspase 9 Mediated Apoptosis: A Multimodal Therapeutic Target in Traumatic Brain Injury
por: Unnisa, Aziz, et al.
Publicado: (2023)

Melatonin as an Antioxidant Agent in Stroke: An Updated Review
por: Wang, Junjie, et al.
Publicado: (2022)

Mitochondrial Dynamics: A Potential Therapeutic Target for Ischemic Stroke
por: Zhou, Xiangyue, et al.
Publicado: (2021)

Ferroptosis in glioma treatment: Current situation, prospects and drug applications
por: Zhou, Yuhang, et al.
Publicado: (2022)

The Connection Between Selected Caspases Levels in Bronchoalveolar Lavage Fluid and Severity After Brain Injury
por: Siwicka-Gieroba, Dorota, et al.
Publicado: (2022)

The role of the astrocyte in subarachnoid hemorrhage and its therapeutic implications
por: Li, Rong, et al.
Publicado: (2022)

Targeting parvalbumin promotes M2 macrophage polarization and energy expenditure in mice
por: Lin, Shaojian, et al.
Publicado: (2022)

Editorial: Current and Future Developments in the Therapeutic Management of Neuromuscular Diseases
por: Papadimas, George K., et al.
Publicado: (2022)

Pituitary Adenylate Cyclase-Activating Polypeptide: A Promising Neuroprotective Peptide in Stroke
por: Fang, Yuanjian, et al.
Publicado: (2020)

Inhibition of Aryl Hydrocarbon Receptor Attenuates Hyperglycemia‐Induced Hematoma Expansion in an Intracerebral Hemorrhage Mouse Model
por: Ren, Reng, et al.
Publicado: (2021)

Is There a Future for Non-invasive Brain Stimulation as a Therapeutic Tool?
por: Terranova, Carmen, et al.
Publicado: (2019)

URB2 as an important marker for glioma prognosis and immunotherapy
por: Fang, Chaoyou, et al.
Publicado: (2023)

Changes of Functional, Morphological, and Inflammatory Reactions in Spontaneous Peripheral Nerve Reinnervation after Thermal Injury
por: Yu, Xing, et al.
Publicado: (2022)

Editorial: New insights into the treatment of aneurysms with flow diverters: novel indications and therapeutic advances
por: Zhou, Yu, et al.
Publicado: (2023)

Protective effect of c-Myc/Rab7a signal pathway in glioblastoma cells under hypoxia
por: Li, Chenguang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_s968il8ct4ak2nsggogbnkhlke