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Release of nanodiscs from charged nano-droplets in the electrospray ionization revealed by molecular dynamics simulations

Electrospray ionization (ESI) is essential for application of mass spectrometry in biological systems, as it prevents the analyte being split into fragments. However, due to lack of a clear understanding of the mechanism of ESI, the interpretation of mass spectra is often ambiguous. This is a partic...

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Detalles Bibliográficos
Autores principales: Wang, Beibei, Tieleman, D. Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886951/
https://www.ncbi.nlm.nih.gov/pubmed/36717705
http://dx.doi.org/10.1038/s42004-023-00818-4