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Severe gestational diabetes mellitus in lean dams is associated with low IL-1α levels and affects the growth of the juvenile mouse offspring

We investigated how maternal gestational diabetes (GDM) impacts the metabolic status of offspring. GDM was induced in CD1 mice consuming a fast-food diet (FFD) by repeated low-dose streptozotocin injections before mating. Offspring of normoglycemic standard chow or the FFD consuming dams served as c...

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Detalles Bibliográficos
Autores principales: Mihalovičová, Lucia, Kunšteková, Veronika, Miláček, Dávid, Janko, Jakub, Pastorek, Michal, Konečná, Barbora, Gurecká, Radana, Rausová, Zuzana, Uličná, Oľga, Celec, Peter, Šebeková, Katarína
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886986/
https://www.ncbi.nlm.nih.gov/pubmed/36717684
http://dx.doi.org/10.1038/s41598-023-28903-7