Cargando…
Gastrodin attenuates renal injury and collagen deposition via suppression of the TGF-β1/Smad2/3 signaling pathway based on network pharmacology analysis
Background: Gastrodin has been widely used clinically in China as an antihypertensive drug. However, its effect on hypertensive renal injury is yet to be elucidated. The current study aimed to investigate the effects of gastrodin on hypertensive renal injury and its underlying mechanisms by network...
Autores principales: | Wen, Ying, Zhang, Xiuli, Wei, Lihui, Wu, Meizhu, Cheng, Ying, Zheng, Huifang, Shen, Aling, Fu, Changgeng, Ali, Farman, Long, Linzi, Lu, Yao, Li, Jiapeng, Peng, Jun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887022/ https://www.ncbi.nlm.nih.gov/pubmed/36733505 http://dx.doi.org/10.3389/fphar.2023.1082281 |
Ejemplares similares
-
Gastrodin attenuates angiotensin II-induced vascular contraction and MLCK/p-MLC(2) pathway activation
por: Guo, Zhi, et al.
Publicado: (2023) -
Qingda Granule Attenuates Angiotensin II-Induced Renal Apoptosis and Activation of the p53 Pathway
por: Long, Linzi, et al.
Publicado: (2022) -
Qingda Granule Attenuates Angiotensin II-Induced Blood Pressure and Inhibits Ca(2+)/ERK Signaling Pathway
por: Wu, Meizhu, et al.
Publicado: (2021) -
Based on network pharmacology, gastrodin attenuates hypertension-induced vascular smooth muscle cell proliferation and PI3K/AKT pathway activation
por: Shen, Aling, et al.
Publicado: (2023) -
Quercetin inhibits angiotensin II-induced vascular smooth muscle cell proliferation and activation of JAK2/STAT3 pathway: A target based networking pharmacology approach
por: Wang, Di, et al.
Publicado: (2022)