PFKFB3 overexpression in monocytes of patients with colon but not rectal cancer programs pro-tumor macrophages and is indicative for higher risk of tumor relapse

INTRODUCTION: Circulating monocytes are main source for tumor-associated macrophages (TAMs) that control tumor growth, angiogenesis, metastasis and therapy resistance. We raised the questions how monocyte programming is affected by growing tumors localized in colon and rectal sections, and how treat...

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Detalles Bibliográficos
Autores principales: Larionova, Irina, Patysheva, Marina, Iamshchikov, Pavel, Kazakova, Elena, Kazakova, Anna, Rakina, Militsa, Grigoryeva, Evgeniya, Tarasova, Anna, Afanasiev, Sergei, Bezgodova, Natalia, Kiselev, Artem, Dobrodeev, Alexey, Kostromitskiy, Dmitriy, Cherdyntseva, Nadezhda, Kzhyshkowska, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887047/
https://www.ncbi.nlm.nih.gov/pubmed/36733385
http://dx.doi.org/10.3389/fimmu.2022.1080501

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